ArticleHealth science reports2021
The effect of zinc supplementation on fatigue among elderly community dwellers: A parallel clinical trial.
Article in Health science reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Arsenic disrupts autophagosome-lysosome fusion in a zinc dependent manner across multiple human skin and lung cells lines.Archives of toxicology · 2026Article
- Vitamin and mineral supplements and fatigue: a prospective study.European journal of nutrition · 2025Article
- Severe Dietary Zinc Deficiency Does Not Significantly Alter Energy Balance in Adult Mice.Journal of nutrition and metabolism · 2025Article
- Calcium's Role and Signaling in Aging Muscle, Cellular Senescence, and Mineral Interactions.International journal of molecular sciences · 2023Review
- Nutrient Therapy for the Improvement of Fatigue Symptoms.Nutrients · 2023Review
- Zinc supplementation prevents mitotic accumulation in human keratinocyte cell lines upon environmentally relevant arsenic exposure.Toxicology and applied pharmacology · 2022Article
- The effect of zinc supplementation on fatigue among elderly community dwellers: A parallel clinical trial.Health science reports · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsFatigue is one of the most common complaints of the elderly. This study was conducted to assess the effect of zinc supplements on fatigue among the elderly.
methodsThis randomized clinical trial was conducted on 150 elderly aged ≥60 years who were recruited from the health centers (Kashan, Iran) with a convenience sampling method. Participants were allocated to intervention and control groups by block randomization. Participants in the intervention group received a daily dose of 30 mg of zinc supplement for 70 days; meanwhile, in the control group, no intervention was performed. The level of fatigue was measured by the multidimensional fatigue inventory before and after the intervention. Both groups were homogeneous in terms of demographic variables, fatigue, and serum zinc level before the intervention. The significance level was considered as 0.05 in all tests.
resultsZinc supplementation significantly reduced fatigue (mean difference: -10.41 vs 1.37,
conclusionConsumption of zinc supplements for the elderly is recommended to overcome fatigue.
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Registered trials
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