Evidence map›Paper›PMID 34027086›Full record

ArticleBioengineering & translational medicine2021

Engineered macrophage membrane-enveloped nanomedicine for ameliorating myocardial infarction in a mouse model.

Yugang Xue, Guangwei Zeng, Jin Cheng, Jianqiang Hu, Mingming Zhang, Yan Li

Open access · goldAbstract read
In one paragraph

Article in Bioengineering & translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 43 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Yugang XueDepartment of Cardiology Tangdu Hospital, Air force Military Medical University Xi'an Shaanxi China.
Guangwei ZengSection 2, Department of Cardiology Xi'An International Medical Center Hospital Xi'an Shaanxi China.ORCID https://orcid.org/0000-0001-7025-1209
Jin ChengDepartment of Cardiology Tangdu Hospital, Air force Military Medical University Xi'an Shaanxi China.
Jianqiang HuDepartment of Cardiology Tangdu Hospital, Air force Military Medical University Xi'an Shaanxi China.
Mingming ZhangDepartment of Cardiology Tangdu Hospital, Air force Military Medical University Xi'an Shaanxi China.
Yan LiDepartment of Cardiology Tangdu Hospital, Air force Military Medical University Xi'an Shaanxi China.ORCID https://orcid.org/0000-0003-0096-0813
Tang Du Hospital · CNMedical Center Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myocardial infarction (MI) is the serious condition causing lots of death over the world. Myocytes apoptosis, inflammation, and fibrosis are three important factors implicated in pathogenesis of MI. Targeting these three factors has been shown to ameliorate MI and rescue cardiac function. Previous studies have demonstrated that microRNA (miR) 199a-3p protect against MI. In this study, we prepare macrophage membrane coated nanoparticles (MMNPs) containing miR199a-3p. We evaluate the effects of these NPs on apoptosis and cell proliferation

Indexed as

macrophage membranemicemyocardial infarctionnanomedicine

Identifiers

PMID34027086
PMCPMC8126824
OpenAlexW3100752372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.