Evidence map›Paper›PMID 34026599›Full record

ArticleFrontiers in oncology2021

Resistance Profile of Osimertinib in Pre-treated Patients With EGFR T790M-Mutated Non-small Cell Lung Cancer.

Maria Gabriela O Fernandes, Catarina Sousa, Maria Jacob, Leonor Almeida, Vanessa Santos, David Araújo, Hélder Novais Bastos, Adriana Magalhães, Luís Cirnes, Conceição Souto Moura and 3 more

Abstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Liquid biopsy in modern medicine: advancing diagnostics from molecular insights to clinical practice.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  3. Article
  4. The integrated comprehension of lncRNA HOXA-AS3 implication on human diseases.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maria Gabriela O FernandesPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Catarina SousaPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Maria JacobPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Leonor AlmeidaPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Vanessa SantosPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
David AraújoPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Hélder Novais BastosPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Adriana MagalhãesPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Luís CirnesInstitute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Porto, Portugal.
Conceição Souto MouraPathology Department, Centro Hospitalar Universitário de São João, Porto, Portugal.
Henrique QueirogaPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.
Natália Cruz-MartinsFaculty of Medicine, University of Porto, Porto, Portugal.
Venceslau HespanholPulmonology Department, Centro Hospitalar e Universitário de São João, Porto, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

EGFR T790M mutationnext generation sequencingnon-small cell lung cancerosimertinibreal-world dataresistance

Identifiers

PMID34026599
PMCPMC8136429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.