Evidence map›Paper›PMID 34026474›Full record

ArticleMedical mycology case reports2021

Julien Gras, Yanis Tamzali, Blandine Denis, Maud Gits-Muselli, Stéphane Bretagne, Marie-Noëlle Peraldi, Jean-Michel Molina

Open access · goldAbstract read
In one paragraph

Article in Medical mycology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Specificities of Meningitis and Meningo-Encephalitis After Kidney Transplantation: A French Retrospective Cohort Study.Transplant international : official journal of the European Society for Organ Transplantation · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Julien GrasInfectious Diseases Department, APHP, Saint-Louis Hospital, Paris, France.
Yanis TamzaliInfectious Diseases Department, APHP, Saint-Louis Hospital, Paris, France.
Blandine DenisInfectious Diseases Department, APHP, Saint-Louis Hospital, Paris, France.
Maud Gits-MuselliParasitology and Mycology Department, APHP, Saint-louis Hospital, Paris, France.
Stéphane BretagneParasitology and Mycology Department, APHP, Saint-louis Hospital, Paris, France.
Marie-Noëlle PeraldiNephrology and Kidney Transplant Department, APHP, Saint-louis Hospital, Paris, France.
Jean-Michel MolinaInfectious Diseases Department, APHP, Saint-Louis Hospital, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cryptococcosis is the third most common invasive fungal infection in solid organ transplant recipients. We describe three cases of neuro-meningeal cryptococcosis occurring among kidney transplant (KT) patients, and discuss the diagnostic and therapeutic challenges in this context. Median time from KT to infection was 6 months [range: 3-9]. The most common clinical manifestations at diagnosis were fever (2/3), headache (2/3), and confusion (2/3); none had extra-neurological involvement. CrAg was positive in all cases at diagnosis both in serum and cerebrospinal fluid (CSF). For two patients, analysis of previous samples showed that CrAg was detected in plasma up to 4 weeks before diagnosis. All patients received induction treatment with liposomal amphotericin-B (L-AmB) and flucytosine for a median duration of 10 days [range: 7-14], followed by fluconazole maintenance therapy. Acute kidney injury secondary to L-AmB therapy was observed in only one case, but all patients had a tacrolimus overdose following initiation of maintenance therapy due to drug-drug interactions between fluconazole and tacrolimus. Among KTR, early detection of

Indexed as

CryptococcosisEarly diagnosisGraft functionKidney transplantationMeningitis

Identifiers

PMID34026474
PMCPMC8120857
OpenAlexW3159291010

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.