Evidence map›Paper›PMID 34026454›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Toxicogenomic Profiling of 28 Nanomaterials in Mouse Airways.

Pia A S Kinaret, Joseph Ndika, Marit Ilves, Henrik Wolff, Gerard Vales, Hannu Norppa, Kai Savolainen, Tiina Skoog, Juha Kere, Sergio Moya and 5 more

Open access · goldAbstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. A New Look at the Effects of Engineered ZnO and TiONanomaterials (Basel, Switzerland) · 2022
    Review
  13. Nextcast: A software suite to analyse and model toxicogenomics data.Computational and structural biotechnology journal · 2022
    Article
  14. Toxicogenomic Profiling of 28 Nanomaterials in Mouse Airways.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 4 countries.

Pia A S KinaretInstitute of Biotechnology, Helsinki Institute of Life Science University of Helsinki Helsinki 00790 Finland.
Joseph NdikaHuman Microbiome Research Program (HUMI) University of Helsinki Helsinki 00014 Finland.
Marit IlvesHuman Microbiome Research Program (HUMI) University of Helsinki Helsinki 00014 Finland.
Henrik WolffFinnish Institute of Occupational Health Helsinki 00250 Finland.
Gerard ValesFinnish Institute of Occupational Health Helsinki 00250 Finland.
Hannu NorppaFinnish Institute of Occupational Health Helsinki 00250 Finland.
Kai SavolainenFinnish Institute of Occupational Health Helsinki 00250 Finland.
Tiina SkoogDepartment of Biosciences and Nutrition Karolinska Institutet Stockholm 141 83 Sweden.
Juha KereDepartment of Biosciences and Nutrition Karolinska Institutet Stockholm 141 83 Sweden.
Sergio MoyaCenter for Cooperative Research in Biomaterials (CIC biomaGUNE) Basque Research and Technology Alliance (BRTA) Donostia-San Sebastián 20014 Spain.
Richard D HandySchool of Biological & Marine Sciences University of Plymouth Plymouth PL4 8AA UK.
Piia KarisolaHuman Microbiome Research Program (HUMI) University of Helsinki Helsinki 00014 Finland.
Bengt FadeelInstitute of Environmental Medicine Karolinska Institutet Stockholm 171 77 Sweden.
Dario GrecoInstitute of Biotechnology, Helsinki Institute of Life Science University of Helsinki Helsinki 00790 Finland.
Harri AleniusHuman Microbiome Research Program (HUMI) University of Helsinki Helsinki 00014 Finland.ORCID 0000-0003-0106-8923
University of Helsinki · FIFinnish Institute of Occupational Health · FIKarolinska Institutet · SECIC biomaGUNE · ESUniversity of Plymouth · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Toxicogenomics opens novel opportunities for hazard assessment by utilizing computational methods to map molecular events and biological processes. In this study, the transcriptomic and immunopathological changes associated with airway exposure to a total of 28 engineered nanomaterials (ENM) are investigated. The ENM are selected to have different core (Ag, Au, TiO

Indexed as

AnimalsFemaleLungMiceMice, Inbred C57BLModels, AnimalNanostructuresToxicogeneticsTranscriptomeairway exposureimmunotoxicitynanomaterialsnanoparticlesnanotoxicologytoxicogenomicstranscriptomics

Identifiers

PMID34026454
PMCPMC8132046
OpenAlexW3135303713

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.