Evidence map›Paper›PMID 34026445›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Machine Learning Identifies Metabolic Signatures that Predict the Risk of Recurrent Angina in Remitted Patients after Percutaneous Coronary Intervention: A Multicenter Prospective Cohort Study.

Song Cui, Li Li, Yongjiang Zhang, Jianwei Lu, Xiuzhen Wang, Xiantao Song, Jinghua Liu, Kefeng Li

Abstract readMulticenter Study
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Exploring the Efficacy and Target Genes ofCurrent issues in molecular biology · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Progress in the Metabolomics of Acute Coronary Syndrome.Reviews in cardiovascular medicine · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Perturbations in cardiac metabolism in a human model of acute myocardial ischaemia.Metabolomics : Official journal of the Metabolomic Society · 2021
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Song CuiDepartment of Cardiology Beijing Anzhen Hospital Capital University of Medical Sciences Beijing 100029 China.
Li LiDepartment of Cardiology Qufu People's Hospital Qufu Shandong 273100 China.
Yongjiang ZhangDepartment of Cardiology Qufu People's Hospital Qufu Shandong 273100 China.
Jianwei LuDepartment of Cardiology Qufu People's Hospital Qufu Shandong 273100 China.
Xiuzhen WangDepartment of Cardiology Qufu People's Hospital Qufu Shandong 273100 China.
Xiantao SongDepartment of Cardiology Beijing Anzhen Hospital Capital University of Medical Sciences Beijing 100029 China.
Jinghua LiuDepartment of Cardiology Beijing Anzhen Hospital Capital University of Medical Sciences Beijing 100029 China.
Kefeng LiSchool of Medicine University of California San Diego CA 92093 USA.ORCID 0000-0002-7233-4347

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recurrent angina (RA) after percutaneous coronary intervention (PCI) has few known risk factors, hampering the identification of high-risk populations. In this multicenter study, plasma samples are collected from patients with stable angina after PCI, and these patients are followed-up for 9 months for angina recurrence. Broad-spectrum metabolomic profiling with LC-MS/MS followed by multiple machine learning algorithms is conducted to identify the metabolic signatures associated with future risk of angina recurrence in two large cohorts (

Indexed as

Machine LearningMetabolomeAngina, StableBiomarkersChromatography, LiquidFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionProspective StudiesRecurrenceRisk AssessmentRisk FactorsTandem Mass SpectrometryBiomarkersmachine learningmetabolomicspredictomesrecurrent anginarisk stratification

Identifiers

PMID34026445
PMCPMC8132066

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.