Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 2 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
15 authors at 3 institutions in 1 country.
Shaoxuan ChenState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Kunkun ZhangState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Boxin ZhangState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Mengyun JiangState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Xue ZhangXiang'an Hospital of Xiamen University School of Medicine Xiamen 361102 China.
Yi GuoState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Yingying YuState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Tianyu QinState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Hongda LiState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Qiang ChenState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Zhiyu CaiState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Site LuoKey Laboratory of Ministry of Education for Coast and Wetland Ecosystems College of the Environment and Ecology Xiamen University Xiamen 361102 China.
Yi HuangDepartment of Clinical Laboratory Fujian Provincial Hospital Fuzhou 350001 China.
Jin HuState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.
Wei MoState Key Laboratory of Cellular Stress Biology The First Affiliated Hospital of Xiamen University School of Life Sciences Xiamen University Xiamen 361102 China.ORCID 0000-0002-8165-4473
First Affiliated Hospital of Xiamen University · CNXiamen University · CNFujian Medical University · CN
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Forming tight interaction with both Purkinje and granule cells (GCs), Bergmann glia (BG) are essential for cerebellar morphogenesis and neuronal homeostasis. However, how BG act in this process is unclear without comprehensive transcriptome landscape of BG. Here, high temporal-resolution investigation of transcriptomes with FACS-sorted BG revealed the dynamic expression of genes within given functions and pathways enabled BG to assist neural migration and construct neuron-glia network. It is found that the peak time of GCs migration (P7-10) strikingly coincides with the downregulation of extracellular matrix (ECM) related genes, and the disruption of which by Setdb1 ablation at P7-10 in BG leads to significant migration defect of GCs emphasizing the criticality of Nfix-Setdb1 mediated H3K9me3 repressive complex for the precise regulation of GCs migration in vivo. Thus, BG's transcriptomic landscapes offer an insight into the mechanism by which BG are in depth integrated in cerebellar neural network.
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Temporarily Epigenetic Repression in Bergmann Glia Regulates the Migration of Granule Cells. · full record | OpenQuestion