Evidence map›Paper›PMID 34026397›Full record

ArticleThe mental health clinician2021

The use of the ketogenic diet in the treatment of psychiatric disorders.

Erika E Tillery, Katie D Ellis, Tiffaney B Threatt, Hannah A Reyes, Christopher S Plummer, Logan R Barney

Open access · goldAbstract read
In one paragraph

Article in The mental health clinician, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Human gut microbiome, diet, and mental disorders.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Ketogenic Diet and Inflammation: Implications for Mood and Anxiety Disorders.Advances in experimental medicine and biology · 2023
    Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. The Ketogenic Diet and Alzheimer's Disease.The journal of nutrition, health & aging · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Erika E TilleryAssistant Professor, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0002-6281-550X
Katie D EllisAssistant Professor, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0002-1360-1812
Tiffaney B ThreattAssociate Professor, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0003-3454-739X
Hannah A ReyesStudent, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0003-0821-3353
Christopher S PlummerStudent, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0002-4000-399X
Logan R BarneyStudent, Presbyterian College School of Pharmacy, Clinton, South Carolina.ORCID https://orcid.org/0000-0002-2066-6243
Presbyterian College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe ketogenic diet (KD) is a high-fat, low-carbohydrate, and moderate-protein diet that has shown benefit as a treatment in neurologic disorders and may serve as a therapeutic option in individuals with psychiatric disorders.

methodsA search was conducted using EBSCOhost and PubMed databases for studies relating to ketogenic or low-carbohydrate diets and psychiatric disorders.

resultsA total of 32 experimental or observational studies were identified by initial search strategies, 14 of which met the criteria to be included in this analysis. Although specific diet formulations varied somewhat between studies, they all generally examined low-carbohydrate dietary intake with the goal of producing a ketotic state. The studies included in this review indicated the KD was beneficial in reducing symptoms associated with various psychiatric disorders. DISCUSSION: This review summarizes the available evidence regarding the efficacy of the ketogenic diet in psychiatric disease states. Data from the studies analyzed demonstrated a positive response in individuals who were able to remain on the diet, regardless of the disease state. However, there is a need for more data to clearly define the specific benefits the KD may provide.

Indexed as

ketogenic dietlow carbohydrate dietpsychiatric disorder

Identifiers

PMID34026397
PMCPMC8120987
OpenAlexW3163075298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.