Evidence map›Paper›PMID 34026293›Full record

ArticleJournal of advanced research2021

Genomics-guided identification of a conserved CptBA-like toxin-antitoxin system in

Shahira A ElBanna, Nayera A Moneib, Ramy K Aziz, Reham Samir

Open access · goldAbstract read
In one paragraph

Article in Journal of advanced research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. The role of toxin-antitoxin systems inJournal of bacteriology · 2026
    Review
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  9. PromisingFrontiers in immunology · 2022
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Shahira A ElBannaDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.
Nayera A MoneibDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.
Ramy K AzizDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.
Reham SamirDepartment of Microbiology and Immunology, Faculty of Pharmacy, Cairo University, 11562 Cairo, Egypt.
Cairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Toxin-antitoxin (TA) systems are widespread among bacteria, archaea and fungi. They are classified into six types (I-VI) and have recently been proposed as novel drug targets. Objectives: This study aimed to screen the pathogen Methods: In silico methods included secondary structure prediction, comparative genomics, multiple sequence alignment, and phylogenetic analysis, while Results: Comparative genomics demonstrated the distribution of CptBA-like systems among Gram-negative bacteria, while phylogenetic analysis delineated two major groups, in each of which Conclusion: Combining in silico and

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ToxinsComputational BiologyDrug Resistance, Multiple, BacterialEscherichia coliGenes, BacterialGenome, BacterialGenomicsPhylogenyPlasmidsToxin-Antitoxin SystemsAnti-Bacterial AgentsBacterial ToxinsAcinetobacter baumanniiAntimicrobial resistanceBioinformaticsMolecular biologyPlasmidsStress factorsToxin-antitoxin

Identifiers

PMID34026293
PMCPMC8132199
OpenAlexW3106716287

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.