Evidence map›Paper›PMID 34026155›Full record

ArticleClinical case reports2021

Arsenic toxicity manifesting as profuse watery diarrhea during induction therapy for acute promyelocytic leukemia.

Ashley Ott, Vinayak Venkataraman, Yousef R Badran, Rose Goldman, Smiljana Spasic, Darshali A Vyas, Philip Amrein, Steven McAfee, Andrew Brunner, Amir T Fathi and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Clinical case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ashley OttDepartment of Medicine Massachusetts General Hospital Boston MA USA.ORCID https://orcid.org/0000-0002-4675-6503
Vinayak VenkataramanDepartment of Medicine Massachusetts General Hospital Boston MA USA.
Yousef R BadranDivision of Gastroenterology Department of Medicine Massachusetts General Hospital Boston MA USA.
Rose GoldmanDepartment of Environmental Health Harvard T.H. Chan School of Public Health Boston MA USA.
Smiljana SpasicDepartment of Pathology Massachusetts General Hospital Boston MA USA.
Darshali A VyasDepartment of Medicine Massachusetts General Hospital Boston MA USA.
Philip AmreinDivision of Hematology/Oncology Massachusetts General Hospital Boston MA USA.
Steven McAfeeDivision of Hematology/Oncology Massachusetts General Hospital Boston MA USA.
Andrew BrunnerDivision of Hematology/Oncology Massachusetts General Hospital Boston MA USA.
Amir T FathiDivision of Hematology/Oncology Massachusetts General Hospital Boston MA USA.
Rupa NarayanDivision of Hematology/Oncology Massachusetts General Hospital Boston MA USA.
Harvard University · USMassachusetts General Hospital · USCambridge Health Alliance · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Arsenic trioxide (ATO) is generally well tolerated for treatment of APL. We present a patient with severe watery diarrhea and pancreatitis thought to be due to ATO toxicity in the setting of obesity and acute kidney injury. Future studies evaluating ATO levels in patients experiencing toxicities may help guide dose modifications.

Indexed as

APLAPMLarsenicdiarrheaobesityrenal insufficiency

Identifiers

PMID34026155
PMCPMC8122218
OpenAlexW3161877706

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.