Evidence map›Paper›PMID 34025885›Full record

ArticleRadiology case reports2021

Myocarditis following COVID-19 vaccination.

Elisabeth Albert, Gerard Aurigemma, Jason Saucedo, David S Gerson

Erratum issuedAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 87 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
87citing papers in PubMed, 10 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

87 citing papers in PubMed, 10 syntheses or guidelines pooled it.

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  10. COVID-19 Vaccine and Myocarditis.The American journal of cardiology · 2021
    Pooled it
  11. "Bridging the clinical, molecular and genetic perspectives on myocarditis in post-COVID-19 era".International journal of cardiology. Cardiovascular risk and prevention · 2026
    Review
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  20. Determinants of COVID-19 vaccine-induced myocarditis.Therapeutic advances in drug safety · 2024
    Article

27 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Elisabeth AlbertDepartment of Radiology University of Massachusetts Medical School, UMass Memorial Medical Center, 55 Lake avenue North, Worcester, 01655, MA, USA.
Gerard AurigemmaDepartment of Medicine (Cardiovascular Medicine Division), University of Massachusetts Medical Center, UMass Memorial Medical Center, 55 Lake avenue North Worcester, 01655, MA, USA.
Jason SaucedoDepartment of Medicine (Cardiovascular Medicine Division), University of Massachusetts Medical Center, UMass Memorial Medical Center, 55 Lake avenue North Worcester, 01655, MA, USA.
David S GersonDepartment of Radiology University of Massachusetts Medical School, UMass Memorial Medical Center, 55 Lake avenue North, Worcester, 01655, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) vaccination frequently leads to minor side-effects, that may be more intense after the second dose, but more serious side effects have been reported. We report a case of a 24-year-old man who presented to the hospital with acute substernal chest pain, 4 days after his second COVID-19 Moderna vaccination. Laboratory studies revealed elevated troponins and negative viral serologies. Cardiac magnetic resonance imaging (cMRI) demonstrated edema and delayed gadolinium enhancement of the left ventricle in a midmyocardial and epicardial distribution. The patient was diagnosed with myocarditis following Moderna vaccination. Our case report raises concern that myocarditis is a rare side effect of COVID-19 vaccine. Despite our report, it appears that there is a significantly higher risk of cardiac involvement from COVID-19 infection compared to COVID-19 vaccination.

Identifiers

PMID34025885
PMCPMC8130498

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.