Evidence map›Paper›PMID 34025770›Full record

ArticleEvolutionary applications2021

Evolution of honey resistance in experimental populations of bacteria depends on the type of honey and has no major side effects for antibiotic susceptibility.

Anna M Bischofberger, Katia R Pfrunder Cardozo, Michael Baumgartner, Alex R Hall

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Evolutionary applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Honey as a Natural Antimicrobial.Antibiotics (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Manuka honey as a non-antibiotic alternative againstFrontiers in cellular and infection microbiology · 2024
    Review
  7. Article
  8. Article
  9. Erratum.Evolutionary applications · 2022
    Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anna M BischofbergerInstitute of Integrative Biology ETH Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0001-5909-488X
Katia R Pfrunder CardozoInstitute of Integrative Biology ETH Zurich Zurich Switzerland.
Michael BaumgartnerInstitute of Integrative Biology ETH Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0002-4158-460X
Alex R HallInstitute of Integrative Biology ETH Zurich Zurich Switzerland.ORCID https://orcid.org/0000-0002-3654-1373
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With rising antibiotic resistance, alternative treatments for communicable diseases are increasingly relevant. One possible alternative for some types of infections is honey, used in wound care since before 2000 BCE and more recently in licensed, medical-grade products. However, it is unclear whether medical application of honey results in the evolution of bacterial honey resistance and whether this has collateral effects on other bacterial traits such as antibiotic resistance. Here, we used single-step screening assays and serial transfer at increasing concentrations to isolate honey-resistant mutants of

Indexed as

anti‐bacterial agentsbacteriacommunicable diseasesEscherichia colihoneyleptospermummicrobial drug resistance

Identifiers

PMID34025770
PMCPMC8127710
OpenAlexW3128614909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.