Evidence map›Paper›PMID 34025737›Full record

ArticleJournal of contemporary brachytherapy2021

Computed tomography-based flap brachytherapy for non-melanoma skin cancers of the face.

Emile Gogineni, Haocheng Cai, Dawn Carillo, Zaker Rana, Beatrice Bloom, Louis Potters, Hani Gaballa, Maged Ghaly

Open access · goldAbstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Brachytherapy and 3D printing for skin cancer: A review paper.Journal of contemporary brachytherapy · 2024
    Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Emile GogineniDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Haocheng CaiDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Dawn CarilloDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Zaker RanaDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Beatrice BloomDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Louis PottersDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Hani GaballaDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Maged GhalyDepartment of Radiation Medicine, Northwell Health, Lake Success, NY, USA.
Northwell Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNon-melanoma skin cancers of the face are at high-risk for local recurrence and metastatic spread. While surgical interventions such as Mohs microsurgery are considered the standard of care, this modality has the potential for high rates of toxicity in sensitive areas of the face. Catheter flap high-dose-rate (HDR) brachytherapy has shown promising results, with high rates of local control and acceptable cosmetic outcomes. MATERIAL AND

methodsPatients with non-melanoma skin cancers (NMSC) located on the face were treated with 40 Gy in 8 fractions, given twice weekly via catheter flap HDR brachytherapy. Clinical target volume (CTV) included the visible tumor plus a margin of 5 mm in all directions, with no additional planning target volume (PTV) margin.

resultsFifty patients with 53 lesions on the face were included, with a median follow-up of 15 months. All were considered high-risk based on NCCN guidelines. Median tumor size and thickness were 18 mm and 5 mm, respectively. Median PTV volume and D

conclusionsCT-based flap applicator brachytherapy is a valid treatment option for patients with NMSC of the face. This modality offers high rates of local control with acceptable cosmetic outcomes and low rates of toxicity.

Indexed as

brachytherapycatheter flapfaceflapHDRnon-melanomaradiationskin cancer

Identifiers

PMID34025737
PMCPMC8117709
OpenAlexW3133442806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.