Evidence map›Paper›PMID 34025644›Full record

ReviewFrontiers in immunology2021

Modeling Virus-Induced Inflammation in Zebrafish: A Balance Between Infection Control and Excessive Inflammation.

Con Sullivan, Brandy-Lee Soos, Paul J Millard, Carol H Kim, Benjamin L King

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 56 citations in OpenAlex.

  1. Article
  2. Article
  3. Vitamin DApplied microbiology and biotechnology · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Zebrafish as a Model for Translational Immuno-Oncology.Journal of personalized medicine · 2025
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Multi-spectral Fluorescent Reporter Influenza A Viruses Allow forbioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Article
  19. Development and function of chicken XCR1Frontiers in immunology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Con SullivanCollege of Arts and Sciences, University of Maine at Augusta, Bangor, ME, United States.
Brandy-Lee SoosDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, ME, United States.
Paul J MillardDepartment of Environmental and Sustainable Engineering, University at Albany, Albany, NY, United States.
Carol H KimDepartment of Biomedical Sciences, University at Albany, Albany, NY, United States.
Benjamin L KingDepartment of Molecular and Biomedical Sciences, University of Maine, Orono, ME, United States.
University at Albany, State University of New York · USUniversity of Maine · USUniversity of Maine at Augusta · US

Funding

The Maine Biomedical Research Network (INBRE)P20GM103423 · NIGMS · MOUNT DESERT ISLAND BIOLOGICAL LAB · PI Dustin Lynn Updike · 2012 to 2026
$60.0M
Elucidating the Mechanisms of the Neutrophilic Behavior and Hyperinflammatory Response to Influenza InfectionR15AI131202 · NIAID · UNIVERSITY OF MAINE ORONO · PI KING, BENJAMIN L · 2018 to 2018
$435k
NIAID NIH HHS R15 AI131202NIGMS NIH HHS P20 GM103423
6 · The paper itself

Abstract

The inflammatory response to viral infection in humans is a dynamic process with complex cell interactions that are governed by the immune system and influenced by both host and viral factors. Due to this complexity, the relative contributions of the virus and host factors are best studied

Indexed as

AnimalsHomeostasisImmunity, InnateInfection ControlInflammationVirus DiseasesZebrafishinflammationinnate immunityneutrophilsreactive oxidative speciesvirus infectionzebrafish

Identifiers

PMID34025644
PMCPMC8138431
OpenAlexW3159181663

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.