Evidence map›Paper›PMID 34025636›Full record

ArticleFrontiers in immunology2021

Epidermal Growth Factor Modulates Palmitic Acid-Induced Inflammatory and Lipid Signaling Pathways in SZ95 Sebocytes.

Dániel Törőcsik, Fruzsina Fazekas, Szilárd Póliska, Andrea Gregus, Eszter Anna Janka, Katalin Dull, Andrea Szegedi, Christos C Zouboulis, Dóra Kovács

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Dániel TörőcsikDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Fruzsina FazekasDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Szilárd PóliskaGenomic Medicine and Bioinformatic Core Facility, Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Andrea GregusDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Eszter Anna JankaDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Katalin DullDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Andrea SzegediDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Christos C ZouboulisDepartments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane and Faculty of Health Sciences Brandenburg, Dessau, Germany.
Dóra KovácsDepartment of Dermatology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
University of Debrecen · HUMedizinische Hochschule Brandenburg Theodor Fontane · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epidermal growth factor (EGF) acts as a paracrine and autocrine mediator of cell proliferation and differentiation in various types of epithelial cells, such as sebocytes, which produce the lipid-rich sebum to moisturize the skin. However, sebum lipids

Indexed as

Cell LineEpidermal Growth FactorEpithelial CellsHumansInflammationInterleukin-6Palmitic AcidSebaceous GlandsSignal TransductionEpidermal Growth FactorIL6 protein, humanInterleukin-6Palmitic AcidacneEGFpalmitic acidsebocytessebum

Identifiers

PMID34025636
PMCPMC8134683
OpenAlexW3158432644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.