ArticleFrontiers in psychiatry2021
A Study of Novel Exploratory Tools, Digital Technologies, and Central Nervous System Biomarkers to Characterize Unipolar Depression.
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In one paragraph
Article in Frontiers in psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
5.5field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- The Role of Digital Biomarkers in Physiological Signal-Based Depression Assessment: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2026Pooled it
- Beyond the label "major depressive disorder"-detailed characterization of study population matters for EEG-biomarker research.Frontiers in neuroscience · 2025Pooled it
- A Systematic Review of Location Data for Depression Prediction.International journal of environmental research and public health · 2023Pooled it
- Effectiveness of a Biofeedback Intervention Targeting Mental and Physical Health Among College Students Through Speech and Physiology as Biomarkers Using Machine Learning: A Randomized Controlled Trial.Applied psychophysiology and biofeedback · 2024Trial
- A Clinical AI-Based System (MoodMon) for Affective Disorders: Algorithm Development and Validation.JMIR AI · 2026Article
- Variability in self-reported depression symptomology and associated behavioral markers in digital phenotyping.Scientific reports · 2026Article
- Distinguishing Common Digital Phenotyping and Self-Report Parameters for Monitoring and Predicting Depression: Scoping Review.JMIR mHealth and uHealth · 2026Article
- Sensor-Equipped Digital Technologies for Monitoring and Detecting Depressive Disorders: A Systematic Review.Health science reports · 2026Review
- Digital Biomarkers in Depression: Integrating DSM-5-TR Symptomatology and RDoC Psychological Systems.Current psychiatry reports · 2026Review
- Using Smartphone-Tracked Behavioral Markers to Recognize Depression and Anxiety Symptoms: Cross-Sectional Digital Phenotyping Study.JMIR mental health · 2026Article
- The implementation of digital biomarkers in the diagnosis, treatment and monitoring of mood disorders: a narrative review.Frontiers in digital health · 2025Review
- Mobility-Based Smartphone Digital Phenotypes for Unobtrusively Capturing Everyday Cognition, Mood, and Community Life-Space in Older Adults: Feasibility, Acceptability, and Preliminary Validity Study.JMIR human factors · 2024Article
- Innova4Health: an integrated approach for prevention of recurrence and personalized treatment of Major Depressive Disorder.Frontiers in artificial intelligence · 2024Article
- Enhanced classification and severity prediction of major depressive disorder using acoustic features and machine learning.Frontiers in psychiatry · 2024Article
- Validating the efficacy and value proposition of mental fitness vocal biomarkers in a psychiatric population: prospective cohort study.Frontiers in psychiatry · 2024Article
- Wearable technologies for health research: Opportunities, limitations, and practical and conceptual considerations.Brain, behavior, and immunity · 2023Article
- Development and Validation of a Respiratory-Responsive Vocal Biomarker-Based Tool for Generalizable Detection of Respiratory Impairment: Independent Case-Control Studies in Multiple Respiratory Conditions Including Asthma, Chronic Obstructive Pulmonary Disease, and COVID-19.Journal of medical Internet research · 2023Article
- A narrative review of digital biomarkers in the management of major depressive disorder and treatment-resistant forms.Frontiers in psychiatry · 2023Review
- Description of the Method for Evaluating Digital Endpoints in Alzheimer Disease Study: Protocol for an Exploratory, Cross-sectional Study.JMIR research protocols · 2022Article
- Measuring Health-Related Quality of Life With Multimodal Data: Viewpoint.Journal of medical Internet research · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 11 institutions in 5 countries.
Oleksandr SverdlovNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Jelena CurcicNovartis Institutes for Biomedical Research, Basel, Switzerland.
Kristin HannesdottirNovartis Institutes for Biomedical Research, Cambridge, MA, United States.
Liangke GouNovartis Pharmaceuticals Corporation, East Hanover, NJ, United States.
Valeria De LucaNovartis Institutes for Biomedical Research, Basel, Switzerland.
Francesco AmbrosettiNovartis Institutes for Biomedical Research, Basel, Switzerland.
Bingsong ZhangDepartment of Biostatistics, Bioinformatics and Biomathematics, Georgetown University, Washington, DC, United States.
Jens PraestgaardNovartis Institutes for Biomedical Research, Cambridge, MA, United States.
Vanessa VallejoNovartis Institutes for Biomedical Research, Basel, Switzerland.
Andrew DolmanNovartis Institutes for Biomedical Research, Cambridge, MA, United States.
Baltazar Gomez-MancillaNovartis Institutes for Biomedical Research, Basel, Switzerland.
Konstantinos BiliourisNovartis Institutes for Biomedical Research, Cambridge, MA, United States.
Mark DeurinckNovartis Institutes for Biomedical Research, Basel, Switzerland.
Francesca CormackCambridge Cognition, Cambridge, United Kingdom.
John J AndersonNeurotrack Technologies, Inc., Redwood City, CA, United States.
Nicholas T BottDepartment of Medicine, School of Medicine, Stanford University, Stanford, CA, United States.
Ziv PeremenElMindA Ltd., Herzliya, Israel.
Gil IssacharElMindA Ltd., Herzliya, Israel.
Offir LauferElMindA Ltd., Herzliya, Israel.
Dale JoachimSonde Health, Inc., Boston, MA, United States.
Raj R JagesarGroningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, Netherlands.
Niels JongsGroningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, Netherlands.
Martien J KasGroningen Institute for Evolutionary Life Sciences, University of Groningen, Groningen, Netherlands.
Ahnjili ZhuparrisCentre for Human Drug Research, Leiden, Netherlands.
Rob ZuikerCentre for Human Drug Research, Leiden, Netherlands.
Kasper RecourtCentre for Human Drug Research, Leiden, Netherlands.
Zoë ZuilhofCentre for Human Drug Research, Leiden, Netherlands.
Jang-Ho ChaNovartis Institutes for Biomedical Research, Cambridge, MA, United States.
Gabriel E JacobsCentre for Human Drug Research, Leiden, Netherlands.
Novartis (United States) · USCentre for Human Drug Research · NLHewlett-Packard (Israel) · ILNovartis Institutes for BioMedical ResearchNovartis (Switzerland) · CHUniversity of Groningen · NLCambridge Cognition (United Kingdom) · GBGeorgetown University · USLeiden University Medical Center · NLNeurotrack Technologies (United States) · USStanford University · US
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
digital biomarkersmajor depressionmobile healthnovel endpointsvariable selection
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.