Evidence map›Paper›PMID 34025394›Full record

ArticleFrontiers in pharmacology2021

Quercitrin Attenuates Acetaminophen-Induced Acute Liver Injury by Maintaining Mitochondrial Complex I Activity.

Weichen Xiong, Zixin Yuan, Tianshun Wang, Songtao Wu, Yiyi Xiong, Yunfeng Yao, Yanfang Yang, Hezhen Wu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Role of Mitochondrial Complexes in Liver Diseases.Journal of clinical and translational hepatology · 2025
    Review
  5. Quercitrin, the primary active ingredient ofFrontiers in pharmacology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Weichen XiongFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Zixin YuanFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Tianshun WangFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Songtao WuFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Yiyi XiongFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Yunfeng YaoFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Yanfang YangFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Hezhen WuFaculty of Pharmacy, Hubei University of Chinese Medicine, Wuhan, China.
Hubei University of Chinese Medicine · CNShanghai Innovative Research Center of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The flavonoid quercitrin has a strong antioxidant property. It is also reported to have a protective effect on the liver. However, the mechanism by which it exerts a protective effect on the liver is not fully understood. The objective of this article is to confirm the protective effect of quercitrin extracted from Albiziae flos on acetaminophen (APAP)-induced liver injury and to explain its mechanism. In the

Indexed as

acetaminophenacute liver injurycomplex Imitochondrial dysfunctionquercitrinreactive oxygen species

Identifiers

PMID34025394
PMCPMC8131832
OpenAlexW3159613783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.