Evidence map›Paper›PMID 34025349›Full record

ArticleFrontiers in molecular neuroscience2021

The Val66 and Met66 Alleles-Specific Expression of BDNF in Human Muscle and Their Metabolic Responsivity.

Gilmara Gomes de Assis, Jay R Hoffman, Jacek Bojakowski, Eugenia Murawska-Ciałowicz, Paweł Cięszczyk, Eugene V Gasanov

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. TheBrain plasticity (Amsterdam, Netherlands) · 2022
    Pooled it
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  14. A novelFrontiers in molecular neuroscience · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Gilmara Gomes de AssisDepartment of Molecular Biology, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Jay R HoffmanDepartment of Physical Therapy, Ariel University, Ariel, Israel.
Jacek BojakowskiDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Eugenia Murawska-CiałowiczDepartment of Physiology and Biochemistry, Faculty of Physical Education and Sport, University School of Physical Education in Wrocław, Wrocław, Poland.
Paweł CięszczykDepartment of Molecular Biology, Gdansk University of Physical Education and Sport, Gdańsk, Poland.
Eugene V GasanovLaboratory of Neurodegeneration, International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland.
Gdansk University of Physical Education and Sport · PLAriel University · ILInternational Institute of Molecular and Cell Biology · PLMedical University of Warsaw · PLUniversity School of Physical Education in Wroclaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain-derived neurotrophic factor (BDNF) plays an essential role in nervous system formation and functioning, including metabolism. Present only in humans, the "Val66Met" polymorphism of the BDNF gene (

Indexed as

allele-specific gene expressionBDNFmetabolismmRNA levelVal66Met polymorphismVO2max test

Identifiers

PMID34025349
PMCPMC8131668
OpenAlexW3158998054

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.