Observational studyClinical nutrition ESPEN2021
Energy expenditure and feeding practices and tolerance during the acute and late phase of critically ill COVID-19 patients.
Observational study in Clinical nutrition ESPEN, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 44 citations in OpenAlex.
- Time course of energy expenditure in persistent critical illness: a prospective multicentre study.Critical care (London, England) · 2026Observational
- Relationship between nutrition support and clinical outcomes in post-lung transplant patients in intensive care unit settings: A retrospective study.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2026Article
- Increased physical performance after personalised physiotherapy and nutritional counselling in adults with post-COVID-19 condition: a feasibility randomised trial.Communications medicine · 2026Article
- Personalized Nutrition in the Pediatric ICU: Steering the Shift from Acute Stress to Metabolic Recovery and Rehabilitation.Nutrients · 2024Review
- Severe COVID-19 associated hyperglycemia is caused by beta cell dysfunction: a prospective cohort study.Nutrition & diabetes · 2023Article
- Nutritional status of patients with COVID-19 1-y post-ICU stay: A prospective observational study.Nutrition (Burbank, Los Angeles County, Calif.) · 2023Observational
- Inadequate Energy Delivery Is Frequent among COVID-19 Patients Requiring ECMO Support and Associated with Increased ICU Mortality.Nutrients · 2023Article
- COVID-19: Lessons on malnutrition, nutritional care and public health from the ESPEN-WHO Europe call for papers.Clinical nutrition (Edinburgh, Scotland) · 2022Article
- Nutritional intake and gastro-intestinal symptoms in critically ill COVID-19 patients.Clinical nutrition (Edinburgh, Scotland) · 2022Observational
- Association of nitrogen balance trajectories with clinical outcomes in critically ill COVID-19 patients: A retrospective cohort study.Clinical nutrition (Edinburgh, Scotland) · 2022Observational
- Nutrition support practices across the care continuum in a single centre critical care unit during the first surge of the COVID-19 pandemic - A comparison of VV-ECMO and non-ECMO patients.Clinical nutrition (Edinburgh, Scotland) · 2022Observational
- Nutritional therapy for hospitalized patients with COVID-19: A narrative and integrative review.Journal of intensive medicine · 2022Review
- (Epi)transcriptomics in cardiovascular and neurological complications of COVID-19.Journal of molecular and cellular cardiology plus · 2022Review
- Energy requirements for critically ill patients with COVID-19.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2022Review
- The Role of Indirect Calorimetry in Care of the Surgical Patient.Current surgery reports · 2022Review
- Does Route of Full Feeding Affect Outcome among Ventilated Critically Ill COVID-19 Patients: A Prospective Observational Study.Nutrients · 2021Observational
- Prolonged progressive hypermetabolism during COVID-19 hospitalization undetected by common predictive energy equations.Clinical nutrition ESPEN · 2021Article
- Protein requirements for critically ill ventilator-dependent patients with COVID-19.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2021Article
- Nutrition in the Intensive Care Unit-A Narrative Review.Nutrients · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND &
aimsDifferent metabolic phases can be distinguished in critical illness, which influences nutritional treatment. Achieving optimal nutritional treatment during these phases in critically ill patients is challenging. COVID-19 patients seem particularly difficult to feed due to gastrointestinal problems. Our aim was to describe measured resting energy expenditure (mREE) and feeding practices and tolerance during the acute and late phases of critical illness in COVID-19 patients.
methodsObservational study including critically ill mechanically ventilated adult COVID-19 patients. Indirect calorimetry (Q-NRG+, Cosmed) was used to determine mREE during the acute (day 0-7) and late phase (>day 7) of critical illness. Data on nutritional intake, feeding tolerance and urinary nitrogen loss were collected simultaneously. A paired sample t-test was performed for mREE in both phases.
resultsWe enrolled 21 patients with a median age of 59 years [44-66], 67% male and median BMI of 31.5 kg/m
conclusionIn both the acute and late phase, the majority of the patients were hypermetabolic and fed enterally. In the acute phase patients were fed hypocaloric whereas in the late phase this was almost normocaloric, conform ESPEN guidelines. No significant difference in mREE was observed between phases. Hypermetabolism in both phases in conjunction with an increasing loss of urinary nitrogen may indicate that COVID-19 patients remain in a prolonged acute, catabolic phase.
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