Evidence map›Paper›PMID 34024170›Full record

Observational studyThe Journal of international medical research2021

Clinical significance of serum sex hormones in postmenopausal women with vestibular migraine: potential role of estradiol.

Bo Tang, Xiaojun Yu, Wei Jiang, Chuang Zhang, Tao Zhan, Yuqin He

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Focused Update on Migraine and Vertigo Comorbidity.Current pain and headache reports · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. The role of androgens in migraine pathophysiology.Neurobiology of pain (Cambridge, Mass.)
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Bo TangDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.
Xiaojun YuDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.ORCID https://orcid.org/0000-0002-9855-601X
Wei JiangDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.
Chuang ZhangDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.
Tao ZhanDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.
Yuqin HeDepartment of Neurology, The First Hospital of Changsha, Changsha, Hunan, PR China.
The First Hospital of Changsha · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to investigate the role of sex hormones in postmenopausal women with vestibular migraine.

methodsThis observational study included 242 female patients with vestibular migraine who were postmenopausal during April 2017 to December 2019. Serum levels of sex hormones, including estradiol, progesterone, testosterone, follicle-stimulating hormone, luteinizing hormone, and prolactin, were determined by radioimmunoassay. The duration and frequency (every month) of onset of vestibular migraine were recorded. The degree of vestibular migraine was measured by the visual analogue scale.

resultsSerum levels of estradiol, progesterone, and testosterone were significantly lower, while serum prolactin levels were significantly higher in postmenopausal patients with vestibular migraine compared with healthy controls. Serum estradiol levels were negatively correlated with the duration, frequency, and severity of onset of vestibular migraine. Patients with higher serum estradiol levels showed a longer disease-free survival time.

conclusionSex hormones are correlated with vestibular migraine in postmenopausal women. Additionally, estradiol levels are correlated with the duration, frequency, and severity of onset of vestibular migraine, as well as the disease-free survival time.

Indexed as

EstradiolMigraine DisordersFemaleFollicle Stimulating HormoneGonadal Steroid HormonesHumansLuteinizing HormonePostmenopauseProgesteroneProlactinTestosteroneEstradiolFollicle Stimulating HormoneGonadal Steroid HormonesLuteinizing HormoneProgesteroneProlactinTestosteroneestradiolpostmenopausal womanprolactinSex hormonevertigovestibular migraine

Identifiers

PMID34024170
PMCPMC8142534
OpenAlexW3164189351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.