ArticleCirculation research2021
Single-Cell Epigenomics and Functional Fine-Mapping of Atherosclerosis GWAS Loci.
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In one paragraph
Article in Circulation research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 2 pooled it
8.6field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
74 citing papers in PubMed, 2 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- Linking Iris Cis-Regulatory Variants to Primary Angle-Closure Glaucoma Via Clinical Imaging and Multiomics.Investigative ophthalmology & visual science · 2024Pooled it
- FHL5 Controls Vascular Disease-Associated Gene Programs in Smooth Muscle Cells.Circulation research · 2023Pooled it
- Early atherogenesis: In search of etiology.International journal of cardiology. Cardiovascular risk and prevention · 2026Review
- Epigenetic regulation in atherosclerosis and its therapeutic potential.Nature reviews. Cardiology · 2026Review
- Multimodal atlas of human atherosclerosis links granular vascular cell states to coronary artery disease risk.medRxiv : the preprint server for health sciences · 2026Article
- Unraveling Atherosclerosis through Multi-omics: Systematic Insights into the Unique Applications and Clinical Perspectives.Current atherosclerosis reports · 2026Review
- Coronary artery disease risk gene PRDM16 regulates smooth muscle homeostasis.Journal of molecular and cellular cardiology · 2026Article
- Macrophages in human atherosclerotic plaques in the era of single-cell and spatial transcriptomics.ImmunoHorizons · 2026Review
- Multi-omics data integration from patients with carotid stenosis illuminates key molecular signatures of atherosclerotic instability.Genome medicine · 2026Article
- Comprehensive transcriptomics and proteomics analysis of neointima formation in human saphenous vein: implications for bypass graft disease.American journal of physiology. Heart and circulatory physiology · 2026Article
- Single-cell multiome and enhancer connectome of human retinal pigment epithelium and choroid nominate causal variants in macular degeneration.Cell reports · 2026Article
- A Comprehensive Review of Epigenetic Regulation of Vascular Smooth Muscle Cells During Development and Disease.Biomolecules · 2026Review
- LDOC1 connects histone H2B monoubiquitination to tumor cell plasticity in non-small cell lung cancer.Cell communication and signaling : CCS · 2026Article
- Decoding Vascular Cell Diversity: Single-Cell Approaches to Mechanisms of Vascular Disease.Circulation research · 2026Review
- Variant-to-Biomarker Pathways in Peripheral Artery Disease: Multiomics Integration and Clinical Translation.Human mutation · 2026Review
- Precision medicine and personalized nursing in cardiovascular disease: clinical applications and frontier developments.Frontiers in cardiovascular medicine · 2026Review
- Smooth muscle cells in atherosclerosis: essential but overlooked translational perspectives.European heart journal · 2025Review
- Mapping atherogenesis mechanisms in smooth muscle cells by targeting genes linked to coronary artery disease.iScience · 2025Article
- Coronary artery disease-associated variants regulate vascular smooth muscle cell gene expression.Nature cardiovascular research · 2025Article
- Enhancer-targeting CRISPR screens at coronary artery disease loci suggest shared mechanisms of disease risk.medRxiv : the preprint server for health sciences · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Tiit ÖrdA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Kadri Õunap *A. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Lindsey K Stolze *Department of Cellular and Molecular Medicine, The College of Medicine, The University of Arizona, Tucson, AZ (L.K.S., C.E.R.).
Redouane Aherrahrou *Center for Public Health Genomics (R.A., M.C.), University of Virginia, Charlottesville.
Valtteri NurminenA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Anu ToropainenA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Ilakya SelvarajanA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Tapio LönnbergTurku Bioscience Centre, University of Turku and Åbo Akademi University, Finland (T.L.).
Einari AavikA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Seppo Ylä-HerttualaA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
Mete CivelekCenter for Public Health Genomics (R.A., M.C.), University of Virginia, Charlottesville.
Casey E RomanoskiDepartment of Cellular and Molecular Medicine, The College of Medicine, The University of Arizona, Tucson, AZ (L.K.S., C.E.R.).
Minna U KaikkonenA. I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio (T.Ö., K.Õ., V.N., A.T., I.S., E.A., S.Y.-H., M.U.K.).
University of Eastern Finland · FIUniversity of Arizona · USÅbo Akademi University · FICenter for Open Science · USUniversity of Virginia · US
Funding
SOUTHWEST ENVIRONMENTAL HEALTH SCIENCES CENTERP30ES006694 · NIEHS · UNIVERSITY OF ARIZONA · PI George S Watts · 1994 to 2026
$36.7MMechanisms of ERG in Endothelial ActivationR01HL147187 · NHLBI · UNIVERSITY OF ARIZONA · PI ROMANOSKI, CASEY E · 2019 to 2023
$1.9MNHLBI NIH HHS R01 HL147187NIEHS NIH HHS P30 ES006694
Abstract
[Figure: see text].
Indexed as
DNA MethylationEpigenesis, GeneticEpigenomeEpigenomicsPlaque, AtheroscleroticSingle-Cell AnalysisAgedCells, CulturedChromatin Immunoprecipitation SequencingCoronary Artery DiseaseEndothelial CellsFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansLymphocytesatherosclerosiscoronary artery diseasegeneticsgenome-wide association studymyocardial infarction
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.