ArticleInternational urology and nephrology2022
Assessment of kidney function in chronic kidney disease by combining diffusion tensor imaging and total kidney volume.
Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 13 citations in OpenAlex.
- Multiparametric MRI: can we assess renal function differently?Clinical kidney journal · 2025Review
- 3.0 T diffusion tensor imaging and fiber tractography of the testes in nonobstructive azoospermia.Abdominal radiology (New York) · 2024Article
- Monoexponential, biexponential, stretched-exponential and kurtosis models of diffusion-weighted imaging in kidney assessment: comparison between patients with primary aldosteronism and healthy controls.Abdominal radiology (New York) · 2023Article
- Current progress in artificial intelligence-assisted medical image analysis for chronic kidney disease: A literature review.Computational and structural biotechnology journal · 2023Review
- Clinical study on the use of advanced magnetic resonance imaging in lupus nephritis.BMC medical imaging · 2022Article
- Relationship between Acute Respiratory Tract Infection and the Serum 25(OH) D3 Level in Chronic Kidney Disease Patients and Its Prevention and Treatment.BioMed research international · 2022Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveThis study aimed to investigate the value and feasibility of combining fractional anisotropy (FA) values from diffusion tensor imaging (DTI) and total kidney volume (TKV) for the assessment of kidney function in chronic kidney disease (CKD). MATERIALS AND
methodsFifty-one patients were included in this study. All MRI examinations were performed with a 3.0 T scanner. DTI was used to measure FA values, and TKV was obtained from DTI and T2-weighted imaging (T2WI). Patients were divided into three groups (mild, moderate, severe) according to eGFR, which was calculated with serum creatinine. Differences in the FA values of the cortex and medulla were analysed among the three groups, and the relationships of FA values, TKV, and the product of the FA values and TKV with eGFR were analysed. Receiver operating characteristic (ROC) curve analysis was used to compare the diagnostic efficiency of the FA values, TKV, and the product of the FA values and TKV for kidney function in different CKD stages.
resultsMedullary FA values (m-FA), TKV, and the product of the m-FA values and TKV (m-FA-TKV) were significantly correlated with eGFR (r = 0.653, 0.685, and 0.797, respectively; all P < 0.001). ROC curve analysis showed that m-FA-TKV exhibited better diagnostic performance than m-FA values (P = 0.022).
conclusionm-FA-TKV obtained by DTI significantly improves the accuracy of kidney function assessment in CKD patients.
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