Evidence map›Paper›PMID 34023888›Full record

Trial reportAmerican journal of hypertension2021

A Randomized Trial of Home Blood-Pressure Reduction by Alcohol Guidance During Outpatient Visits: OSAKE Study.

Mai Kabayama, Yuya Akagi, Naoko Wada, Atsuko Higuchi, Michio Tamatani, Jun Tomita, Yukako Nakata, Shin Takiuchi, Koichi Yamamoto, Ken Sugimoto and 3 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mai KabayamaDepartment of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.ORCID 0000-0003-1394-1152
Yuya AkagiDepartment of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.
Naoko WadaDepartment of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.
Atsuko HiguchiDepartment of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.
Michio TamataniTamatani Clinic, Osaka, Osaka, Japan.
Jun TomitaToyonaka Watanabe Clinic, Toyonaka, Japan.
Yukako NakataToyonaka Watanabe Clinic, Toyonaka, Japan.
Shin TakiuchiHigashi Takarazuka Satoh Hospital, Takarazuka, Japan.
Koichi YamamotoDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Ken SugimotoDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Ayumi ShintaniDepartment of Medical Statistics, Osaka City University Graduate School of Medicine and Faculty of Medicine, Osaka, Japan.
Hiromi RakugiDepartment of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita, Japan.
Kei KamideDepartment of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate the effectiveness of the nurse-led alcohol guidance to control home blood pressure (HBP) in the morning among male patients with hypertension during outpatient visits.

methodsWe enrolled 53 male patients with an HBP of ≥135/85 mm Hg with excessive drinking (alcohol ≥210 g/week or ≥60 g/day habitually) among outpatients in a randomized trial. Patients were assigned to a nurse-led alcohol guidance intervention or to the control. The primary outcomes were the mean HBP of 5 consecutive days at 6 months and alcohol consumption.

resultsTwenty-eight and 25 patients were randomized to intervention and control groups, respectively (mean age; 62.7 years old and 64.5, respectively). At baseline, the groups were well balanced across most characteristics. At 6 months, the mean HBP was 131/82 mm Hg in the intervention group vs. 145/87 mm Hg in the control group (SBP <0.001, DBP = 0.09). An HBP level of less than 135/85 mm Hg was achieved among 55.6% of the participants in the intervention group vs. 16.7% in the control group (P = 0.004). The alcohol consumption at 6 months was 256 ± 206 g/w vs. 413 ± 260 g/w, respectively (P = 0.020).

conclusionsWe confirmed the effectiveness of the nurse-led alcohol guidance to control the HBP in male patients with hypertension during outpatient visits. PUBLIC TRIALS REGISTRY NUMBER: UMIN000017454 (UMIN Clinical Trials Registry).

Indexed as

EthanolHypertensionAmbulatory CareBlood PressureHumansMaleMiddle AgedTreatment OutcomeEthanolalcohol guidanceblood pressurehome morning blood pressurehypertensionoutpatient

Identifiers

PMID34023888
PMCPMC8557396

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.