ArticleNeurotoxicology and teratology
A socioecological framework for engaging substance-using pregnant persons in longitudinal research: Multi-stakeholder perspectives.
Article in Neurotoxicology and teratology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed, 10 citations in OpenAlex.
- Promoting research engagement among women with addiction: Impact of recovery peer support in a pilot randomized mixed-methods study.Contemporary clinical trials · 2023Trial
- Challenges, Potential Solutions in Recruiting and Retaining Participants for Alcohol Use Disorder Research: A Literature Review.Healthcare (Basel, Switzerland) · 2026Review
- Navigating complexity: understanding the experiences, motivations and challenges of conducting research with perinatal individuals who use opioids and other substances.BMC pregnancy and childbirth · 2026Article
- Perinatal Insights Into Parenting, Pathways, and Addiction (PIPPA): Protocol for a Longitudinal, Strengths-Based Study in Flanders, Belgium.JMIR research protocols · 2026Article
- Experiences of pregnant and postpartum people of color engaged in a randomized clinical trial of medication to treat opioid use disorder during pregnancy: A "Positive Outliers" analysis.Journal of substance use and addiction treatment · 2026Article
- Willingness of pregnant and postpartum women who use marijuana and/or cannabidiol to participate with their offspring in long-term cohort studies: an exploratory study.Frontiers in psychiatry · 2025Article
- Biospecimens in the HEALthy Brain and Child Development (HBCD) Study: Rationale and protocol.Developmental cognitive neuroscience · 2024Article
- Recruitment and retention strategies to promote research engagement among caregivers and their children: A scoping review.Journal of clinical and translational science · 2024Article
- Ecological momentary assessment of heavy episodic drinking in the early postpartum period: A feasibility study.Drug and alcohol dependence reports · 2023Article
- Feasibility and Acceptability of Integrating Digital Screening and Brief Intervention for Substance Use into Home Visiting: Lessons Learned from a Pilot Study.Journal of evidence-based social work (2019)Article
Corrections and comments
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveUnderstanding the impact of substance use during pregnancy on fetal development and child health is essential for designing effective approaches for reducing prenatal substance exposures and improving child outcomes. Research on the developmental impacts of prenatal substance exposure has been limited by legal, ethical, and practical challenges. This study examined approaches to engage substance-using (with an emphasis on opioids) pregnant persons in longitudinal research, from multi-stakeholder perspectives.
methodsThe present study solicited the expertise of 1) an advisory group of community stakeholders, including people with lived experienced of opioid/substance use; and 2) an online survey with content experts. Qualitative analysis examined facilitators and barriers to recruiting and retaining substance-using pregnant persons through a socioecological lens at the individual, interpersonal, organizational, community, and policy levels.
resultsStakeholders (N = 19) prioritized stigma, loss of confidentiality, legal consequences, and instability (e.g., homelessness and poverty) as important barriers that prevent substance-using persons from enrolling in research studies. Of 70 survey respondents, most self-identified as researchers (n = 37), followed by clinicians (n = 19), and 'others' (n = 14). Survey respondents focused on retention strategies that build trusting relationships with participants, including incentives (e.g., transportation and childcare support), participant-friendly study design, and team-related factors, (e.g., attitudes and practices).
conclusionThe stakeholder input and survey data offer key insights strengthening our understanding of facilitators and barriers to research participation, and ways to overcome barriers among substance-using pregnant persons. A socioecological framework can be used to identify and address these factors to increase recruitment and long-term retention of high-risk populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.