Evidence map›Paper›PMID 34023134›Full record

Observational studyVaccine2021

Older adolescents and young adults willingness to receive the COVID-19 vaccine: Implications for informing public health strategies.

Tracie O Afifi, Samantha Salmon, Tamara Taillieu, Ashley Stewart-Tufescu, Janique Fortier, S Michelle Driedger

Open access · hybridAbstract readObservational Study
In one paragraph

Observational study in Vaccine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Global Systematic Scoping Review of Adolescent Factors Associated With COVID-19 Vaccine Hesitancy.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
    Article
  8. 'Is It Safe? Is it not?' A Youth-Led Photovoice Study of Youth Perspectives of COVID-19 Vaccine Confidence.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Tracie O AfifiDepartments of Community Health Sciences and Psychiatry, University of Manitoba, Winnipeg, Canada. Electronic address: tracie.afifi@umanitoba.ca.
Samantha SalmonDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Canada. Electronic address: samantha.salmon@umanitoba.ca.
Tamara TaillieuInstructor and Research Associate, Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada. Electronic address: tamara.taillieu@umanitoba.ca.
Ashley Stewart-TufescuFaculty of Social Work, University of Manitoba, Winnipeg, Canada. Electronic address: ashley.stewart-tufescu@umanitoba.ca.
Janique FortierDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Canada. Electronic address: janique.fortier@umanitoba.ca.
S Michelle DriedgerDepartment of Community Health Sciences, University of Manitoba, Winnipeg, Canada. Electronic address: Michelle.Driedger@umanitoba.ca.
University of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

importanceThe success in ending the COVID-19 pandemic rests partly on the mass uptake of the COVID-19 vaccine. Little work has been done to understand vaccine willingness among older adolescents and young adults. This is important since this age group may be less likely to adhere to public health guidelines.

objectiveTo understand willingness of getting a vaccine and reasons for vaccine hesitancy among a sample of older adolescents and young adults.

designData were from the Well-Being and Experiences study (The WE Study), a longitudinal community-based sample of older adolescents and young adults collected from Winnipeg, Manitoba, Canada from 2017 to 2020 (n = 664).

settingThe study setting was a community-based observational longitudinal study.

participantsParticipants for the study were aged 14 to 17 years old at baseline in 2016-17 (n = 1000). Data were also collected on one parent/caregiver. Waves 2 (n = 747) and 3 (n = 664) were collected in 2019 and 2020, respectively. EXPOSURES: The main exposures were sociodemographic factors, health conditions, COVID-19 knowledge, and adversity history. MAIN OUTCOMES: The main outcomes were COVID-19 vaccine willingness, hesitancy, and reasons for hesitancy.

resultsWillingness to get a COVID-19 vaccine was 65.4%. Willingness did not differ by age, sex, or mental health conditions, but did differ for other sociodemographic characteristics, physical health conditions, COVID-19 knowledge, practicing social/physical distancing, and adversity history. The most common reasons for not wanting a vaccine were related to safety, knowledge, and effectiveness. Sex differences were noted. CONCLUSIONS AND RELEVANCE: Increasing uptake of the COVID-19 vaccine among older adolescents and young adults may rely on targeting individuals from households with lower income, financial burden, and adversity history, and generating public health messaging specifically aimed at vaccine safety, how it works to protect against illness, and why it is important to protect oneself against a COVID-19 infection.

Indexed as

COVID-19VaccinesAdolescentCanadaCOVID-19 VaccinesFemaleHumansLongitudinal StudiesMaleManitobaPandemicsPublic HealthSARS-CoV-2VaccinationYoung AdultCOVID-19 VaccinesVaccinesAdolescentsCOVID-19Public healthVaccine hesitancyYoung adults

Identifiers

PMID34023134
PMCPMC8114588
OpenAlexW3160171540

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.