Evidence map›Paper›PMID 34022956›Full record

ArticleImplementation science communications2021

Implementation determinants and mechanisms for the prevention and treatment of adolescent HIV in sub-Saharan Africa: concept mapping of the NIH Fogarty International Center Adolescent HIV Implementation Science Alliance (AHISA) initiative.

Gregory A Aarons, Kendal Reeder, Nadia A Sam-Agudu, Susan Vorkoper, Rachel Sturke

Erratum issuedAbstract read
In one paragraph

Article in Implementation science communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Gregory A AaronsDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive (0812), La Jolla, CA, 92093-0812, USA. gaarons@health.ucsd.edu.ORCID http://orcid.org/0000-0001-8969-5002
Kendal ReederDepartment of Psychiatry, University of California San Diego, 9500 Gilman Drive (0812), La Jolla, CA, 92093-0812, USA.
Nadia A Sam-AguduInstitute of Human Virology and Department of Pediatrics, University of Maryland School of Medicine, 725 West Lombard Street, Baltimore, MD, 21201, USA.
Susan VorkoperNIH Fogarty International Center, Center for Global Health Studies, Bethesda, MD, USA.
Rachel SturkeNIH Fogarty International Center, Center for Global Health Studies, Bethesda, MD, USA.

Funding

Statewide System and Organizational Strategy for Evidence-Based Practice Implementation and Sustainment in Substance Use Disorder TreatmentR01DA049891 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2020 to 2024
$3.6M
Testing the Leadership and Organizational Change for Implementation (LOCI) Intervention in Substance Abuse Treatment ProgramsR01DA038466 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2015 to 2019
$3.0M
The Adolescent to Adult Patient-centered HIV Transition Study (ADAPT)R01HD089866 · NICHD · UNIVERSITY OF MARYLAND BALTIMORE · PI CHARURAT, MANHATTAN E, SAM-AGUDU, NADIA A. · 2016 to 2021
$1.3M
Development and Testing of an Evidence Based Intervention Sustainment MeasureR03MH117493 · NIMH · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI AARONS, GREGORY · 2018 to 2019
$157k
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD089866FIC NIH HHS ATW14002001-1-0-1NICHD NIH HHS R01 HD089866NIDA NIH HHS R01 DA038466NIDA NIH HHS R01DA038466NIDA NIH HHS R01 DA049891NIDA NIH HHS R01DA049891NIMH NIH HHS R03 MH117493NIMH NIH HHS R03MH117493
6 · The paper itself

Abstract

introductionAdolescent HIV prevention and treatment is a high priority for youth healthcare in sub-Saharan Africa.

methodsThis study employed concept mapping to identify factors that impact the implementation of HIV prevention and intervention programs for adolescents in sub-Saharan Africa. Key stakeholders including researchers, policymakers, and non-governmental organization (NGO) personnel constituting membership of the NIH-sponsored Adolescent HIV Prevention and Treatment Implementation Science Alliance responded to the question: "In your experience, what factors have facilitated or hindered implementation of evidence-based HIV prevention or treatment for adolescents in sub-Saharan Africa?" Participants generated statements in response to the focus question, sorted them into thematically relevant groups, and rated each statement on its importance and changeability.

resultsThrough data analyses and participant feedback, 15 distinct themes were derived. "Workforce/Workflow" and "HIV Stigma and Adolescent Development" were rated highest for importance, and "Threshold Conditions for Treatment" and "Structure of Implementation Efforts" were rated most changeable.

conclusionsUnderstanding implementation science determinants and mechanisms can facilitate the uptake of successful implementation and sustainment strategies for the prevention and treatment of HIV in a given context. We placed determinants and mechanisms within the Exploration, Preparation, Implementation, Sustainment (EPIS) framework to provide greater contextual integration with broader theories in implementation science. Implementers across multiple disciplines can use these findings to improve the scale-up of evidence-based practices for adolescent HIV prevention and treatment in sub-Saharan Africa. Implementation approaches that consider the determinants and mechanisms identified in this study and integrated in implementation frameworks will likely have utility for other health conditions and contexts.

Indexed as

AdolescentAfricaConcept mappingEPIS frameworkHIVImplementation scienceSustainment

Identifiers

PMID34022956
PMCPMC8141156

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.