Evidence map›Paper›PMID 34022950›Full record

ArticleAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology2021

Assessment of changes in genetic transcriptome in nasal epithelial cells exposed to ozone-aged black carbon and pollen allergen by high-throughput transcriptomics.

Yuhui Ouyang, Ying Li, Zhaojun Xu, Yusan An, Luo Zhang

Open access · goldAbstract read
In one paragraph

Article in Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Yuhui OuyangDepartment of Allergy, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, 100730, China.
Ying LiDepartment of Otolaryngology Head and Neck, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, 100730, China.
Zhaojun XuDepartment of Environmental Medicine, Quanzhou Medical College, Quanzhou, 362011, Fujian, China.
Yusan AnDepartment of Otolaryngology Head and Neck, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, 100730, China.
Luo ZhangDepartment of Allergy, Beijing Tongren Hospital, Capital University of Medical Science, Beijing, 100730, China. dr.luozhang@139.com.ORCID http://orcid.org/0000-0002-0910-9884
Beijing Tongren Hospital · CNQuanzhou Normal University · CN

Funding

Beijing Health Bureau Program for High Level Talents 2014-3-017Beijing Municipal Science and Technology Project Z181100001618002Beijing science and technology commission science and technology planning project Z191100009119013
6 · The paper itself

Abstract

backgroundAir pollution may be associated with increased airway responsiveness to allergens in allergic rhinitis (AR). Ozone-aged environmental black carbon (O

methodshNECs from nasal epithelial mucosal samples of healthy individuals undergoing nasal surgery (turbinoplasty or septoplasty) were established as air-liquid interface (ALI) cultures and exposed to O

resultsExposure to ≥ 50 μg/ml O

conclusionO

Indexed as

Differential gene expressionGene OntologyHigh-throughput RNA sequencingHuman nasal epithelial cell (hNECs)InflammationKEGG pathway analysisOzone-aged black carbon (O3BC)Pollen allergenTranscriptome

Identifiers

PMID34022950
PMCPMC8141196
OpenAlexW3112933913

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.