Evidence map›Paper›PMID 34022821›Full record

SynthesisBMC cancer2021

Identifying outcomes reported in exercise interventions in oesophagogastric cancer survivors: a systematic review.

Louise O'Connor, Emily Smyth, Annemarie E Bennett, Valerie Smith, Linda O'Neill, John V Reynolds, Juliette Hussey, Emer Guinan

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Health-related quality of life in esophageal cancer: a state-of-the-art review of patient-reported outcomes and an evidence and gap map.Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Louise O'ConnorDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Emily SmythDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Annemarie E BennettDiscipline of Clinical Medicine, Trinity College Dublin, Dublin, Ireland.
Valerie SmithSchool of Nursing & Midwifery, Trinity College Dublin, Dublin, Ireland.
Linda O'NeillDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
John V ReynoldsDepartment of Survery St James's Hospital and Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland.
Juliette HusseyDiscipline of Physiotherapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Emer GuinanSchool of Medicine, Trinity College Dublin, Dublin, Ireland. emguinan@tcd.ie.ORCID http://orcid.org/0000-0001-9715-146X
Trinity College Dublin · IE

Funding

Health Research Board DIFA-FA-2018-009
6 · The paper itself

Abstract

backgroundResearch investigating exercise interventions in oesophagogastric cancer survivors is sparse, and the outcomes are varied. The aim of this systematic review is to identify the domains and outcomes reported in exercise interventions in oesophagogastric cancer survivors to be included in a Delphi study, with a view to informing the development of a core outcome set (COS).

methodsEMBASE, PubMed, CINHAL, Cochrane Library, SCOPUS, and PEDro were searched up to March 2020 using a predefined search strategy. The outcomes identified during data extraction were categorised using the core areas outlined in the OMERACT Filter 2.0.

resultsFourteen domains and 63 outcomes were identified. The most frequently reported outcomes were in the domains of quality of life using the EORTC-QLQ-C30 questionnaire and the relevant disease-specific modules (100%), exercise capacity/fitness/physical function (100%), anthropometrics (83.33%), physical activity (66.67%), and biomarker analysis (50%).

conclusionThis systematic review quantifies and describes the domains and outcomes examined in exercise interventions in oesophagogastric cancer survivors. Some inconsistency exists within the domains and outcomes used, and little attention was given to nutritional or economic endpoints. In order to develop a COS, a Delphi consensus process with key stakeholders is needed to identify the relevant domains and outcomes for inclusion.

Indexed as

Exercise TherapyPatient Outcome AssessmentCancer SurvivorsClinical Trials as TopicConsensusDelphi TechniqueEsophageal NeoplasmsHumansQuality of LifeStomach NeoplasmsTreatment OutcomeCore outcome setExerciseOesophagogastric cancerRehabilitation

Identifiers

PMID34022821
PMCPMC8141124
OpenAlexW3165288201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.