Evidence map›Paper›PMID 34022755›Full record

ArticleAddictive behaviors2021

Estimating causal and time-varying effects of maternal smoking on youth smoking.

Sooyong Kim, Arielle Selya, Lauren S Wakschlag, Lisa Dierker, Jennifer S Rose, Don Hedeker, Robin J Mermelstein

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Prenatal Substance Exposure.Annual review of developmental psychology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Sooyong KimBehavioral Sciences Group, Sanford Research, Sioux Falls, SD, United States; PinneyAssociates, Inc., Pittsburgh, PA, United States.
Arielle SelyaBehavioral Sciences Group, Sanford Research, Sioux Falls, SD, United States; PinneyAssociates, Inc., Pittsburgh, PA, United States; Department of Pediatrics, University of South Dakota Sanford School of Medicine, Sioux Falls, SD, United States. Electronic address: Arielle.Selya@SanfordHealth.org.
Lauren S WakschlagDepartment of Medical Social Sciences, Feinberg School of Medicine and Institute for Innovations in Developmental Sciences, Northwestern University Chicago, IL, United States.
Lisa DierkerDepartment of Psychology, Wesleyan University, Middletown, CT, United States.
Jennifer S RoseDepartment of Psychology, Wesleyan University, Middletown, CT, United States.
Don HedekerDepartment of Public Health Sciences, University of Chicago, Chicago, IL, United States.
Robin J MermelsteinInstitute for Health Research and Policy, University of Illinois-Chicago, Chicago, IL, United States.
Wesleyan University · USChicago Department of Public Health · US

Funding

Social-Emotional Contexts of Adolescent Smoking PatternsP01CA098262 · NCI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DIVIAK, KATHLEEN · 2004 to 2014
$26.3M
Transdisciplinary approaches to American Indian and rural population health researchP20GM121341 · NIGMS · SANFORD RESEARCH/USD · PI ANGAL, JYOTI · 2017 to 2022
$11.8M
2/2 Optimizing access, engagement and assessment to elucidate prenatal influences on neurodevelopment: The Brains Begin Before Birth(B4 ) Midwest ConsortiumR34DA050266 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WAKSCHLAG, LAUREN S · 2019 to 2020
$687k
NCI NIH HHS P01 CA098262NIDA NIH HHS L40 DA042431NIDA NIH HHS R34 DA050266NIGMS NIH HHS P20 GM121341
6 · The paper itself

Abstract

introductionMaternal smoking is a well-known risk factor for youth smoking, yet whether this relationship is causal remains unresolved. This study utilizes propensity score methods for causal inference to robustly account for shared risk factors between maternal and offspring smoking.

methodsAn 8-year longitudinal cohort of 900 adolescents in the Chicago area were followed starting from approximately age 15.6. The effects of maternal lifetime smoking (MLS) and prenatal tobacco exposure (PTE) (among participants reporting MLS) on offspring's past 30-day smoking, daily smoking status and smoking frequency were examined using logistic regression and Poisson regression after nearest-neighbor propensity matching. Age dependency of this relationship was then examined across the age range of 15-25 using time-varying effect modeling.

resultsPropensity matching yielded 438 and 132 pairs for MLS and PTE study samples, respectively. MLS demonstrated significant associations with past 30-day smoking (RR 1.09; 95% CI 1.04-1.14), daily smoking (RR 1.08; 95% CI 1.05-1.12), and smoking frequency of offspring (RR 1.32; 95% CI 1.15-1.52), with stable effects across age. Among participants reporting MLS, having PTE showed significant additional effects on daily smoking (RR 1.09; 95% CI 1.02-1.17) and age-dependency that showed significance during young adulthood but not adolescence.

conclusionThe relationship between maternal and offspring smoking was not fully accounted for by shared risk factors, suggesting possible causation with PTE having a delayed effect across age. Targeted prevention efforts should be made on maternal smoking-exposed adolescents to mitigate their risks of developing heavy smoking habits in adulthood.

Indexed as

Prenatal Exposure Delayed EffectsTobacco Use DisorderAdolescentAdultChicagoFemaleHumansPregnancyRisk FactorsSmokingTobacco SmokingYoung AdultAdolescentMaternal smokingOffspringPrenatal tobacco exposureSmoking

Identifiers

PMID34022755
PMCPMC8194413
OpenAlexW3159299553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.