Evidence map›Paper›PMID 34022734›Full record

ArticleJournal of infection and public health2021

Prevalence and predictors of in-hospital mortality of patients hospitalized with COVID-19 infection.

Faryal Khamis, Ziad Memish, Maher Al Bahrani, Samata Al Dowaiki, Nenad Pandak, Zakaryia Al Bolushi, Issa Al Salmi, Ibrahim Al-Zakwani

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Article in Journal of infection and public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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32citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Faryal KhamisAdult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman. Electronic address: khami001@gmail.com.
Ziad MemishDirector Research & Innovation Centre, King Saud Medical City, Ministry of Health & College of Medicine, Al Faisal University, Riyadh, Saudi Arabia.
Maher Al BahraniDepartment of Anaesthesia and Critical Care, Department of Medicine, Ministry of Health, Muscat Oman.
Samata Al DowaikiAdult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman.
Nenad PandakAdult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman.
Zakaryia Al BolushiAdult Infectious Diseases, Department of Medicine, Royal Hospital, Ministry of Health, Muscat Oman.
Issa Al SalmiNephrology, Department of Medicine, Royal Hospital, Ministry of Health, Muscat, Oman.
Ibrahim Al-ZakwaniDepartment of Pharmacology & Clinical Pharmacy, College of Medicine & Health Sciences, Sultan Qaboos University, Muscat, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe severity and mortality from COVID-19 infection vary among populations. The aim of this study was to determine the prevalence and predictors of mortality among patients hospitalized with COVID-19 infection in a tertiary care hospital in Oman.

methodsWe conducted a retrospective study using database that included: demographic, clinical characteristics, laboratory parameters, medications and clinical outcomes of all patients hospitalized in Royal Hospital, Muscat, Oman, between March 12, 2020 and December 1st 2020. Univariate and multivariate logistic regression was performed to investigate the relationship between each variable and the risk of death of COVID-19 infected patients.

resultsIn total,1002 patients with COVID-19 infection with mean age of the cohort was 54±16 years (65% (n=650) male) were included, with an overall and intensive care unit (ICU) mortalities of 26% (n=257) and 42% (n=199/473), respectively. The prevalence of ICU admission was 47% (n=473) and the need for mechanical ventilation was 41% (n=413). The overall length of stay in the ICU was 13 (9-21) days. Adjusting for other factors in the model, the multivariable logistic regression demonstrated that in-hospital mortality in admitted COVID-19 patients was associated with old age (p<0.001), heart diseases (adjusted odds ratio (aOR), 1.84; 95% confidence interval (CI): 1.11-3.03; p=0.018), liver diseases (aOR, 4.48; 95% CI: 1.04-19.3; p=0.044), those with higher ferritin levels (aOR, 1.00; 95% CI: 1.00-1.00; p=0.006), acute respiratory distress syndrome (ARDS) (aOR, 3.20; 95% CI: 1.65-6.18; p=0.001), sepsis (aOR, 1.77; 95% CI: 1.12-2.80; p=0.022), and those that had ICU admission (aOR, 2.22; 95% CI: 1.12-4.38; p=0.022).

conclusionIn this cohort, mortality in hospitalized COVID-19 patients was high and was associated with advanced age, heart diseases, liver disease, high ferritin, ARDS, sepsis and ICU admission. These high-risk groups should be prioritized for COVID-19 vaccinations.

Indexed as

COVID-19AdultAgedHospital MortalityHumansIntensive Care UnitsMaleMiddle AgedOmanPrevalenceRespiration, ArtificialRetrospective StudiesRisk FactorsSARS-CoV-2ARDSCOVID-19FerritinHeart diseaseIntensive care unitLiver diseasesMortalitySARS-CoV-2Sepsis

Identifiers

PMID34022734
PMCPMC8053361

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.