ArticleNeurobiology of aging2021
Obesity is associated with reduced cerebral blood flow - modified by physical activity.
Article in Neurobiology of aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Vascular risk factors for idiopathic normal pressure hydrocephalus: a systematic review and meta-analysis.Frontiers in neurology · 2023Pooled it
- Effects of 16 Weeks of Taekwondo Training on the Cerebral Blood Flow Velocity, Circulating Neurotransmitters, and Subjective Well-Being of Obese Postmenopausal Women.International journal of environmental research and public health · 2021Trial
- Effects of obesity on brain health and cognition.Nature reviews. Neurology · 2026Review
- Timing and Duration of Prediabetic Metabolic Dysfunction Differentially Impact Cerebral Perfusion, Vascular Structure, and Behavior.Journal of cardiovascular translational research · 2026Article
- Article
- Obesity as a catalyst for neurodegeneration.Nature metabolism · 2026Review
- Life-course body shape trajectories and cerebral oxygen metabolism in community-dwelling older adults.GeroScience · 2026Article
- Exploratory associations of sleep spindles and sleep disordered breathing indices with hippocampal and thalamic volume, and cortical thickness, and cerebrovascular biomarkers among community dwelling older adults: results from the Brain in Motion Study.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Effects of peanut consumption on task-related brain activation, cognition and neuroinflammation in older adults with memory complaints: a randomized controlled trial.Frontiers in nutrition · 2026Article
- Convergent functional, white-matter microstructural, and cerebral perfusion abnormalities in overweight and obese adults: a multimodal MRI study.Frontiers in nutrition · 2026Article
- Sex-dependent effects of a high-fat diet-induced obesity model on cerebrovascular health and brain metabolism.Experimental physiology · 2025Article
- Characterizing Neurocardiovascular Responses to an Active Stand Test in Older Women: A Pilot Study Using Functional Data Analysis.Sensors (Basel, Switzerland) · 2025Article
- Causal association of obesity and chronic pain mediated by educational attainment and smoking: a mediation Mendelian randomization study.The Korean journal of pain · 2025Article
- Associations between potential risk factors and blood-brain barrier water permeability in middle-aged and older adults.Journal of Alzheimer's disease : JAD · 2025Article
- Examining the independent and moderating effects of arterial stiffness and cerebral blood flow on total hippocampal and hippocampal subfield volumes.Frontiers in aging neuroscience · 2025Article
- Multimodal Imaging-Based Cerebral Blood Flow Prediction Model Development in Simulated Microgravity.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- The interactions between energy homeostasis and neurovascular plasticity.Nature reviews. Endocrinology · 2024Review
- Should We Consider Neurodegeneration by Itself or in a Triangulation with Neuroinflammation and Demyelination? The Example of Multiple Sclerosis and Beyond.International journal of molecular sciences · 2024Review
- Interactive Relations of Body Mass Index, Cardiorespiratory Fitness, and Sex to Cognitive Function in Older Adults.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Exploring the Impact of Hemoglobin on Cerebral Blood Flow in Arterial Territories and Surgical Outcomes: Potential Implications for Moyamoya Disease Treatment.Journal of the American Heart Association · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 3 countries.
Funding
Abstract
This study examined the associations of body mass index (BMI), waist-to-hip ratio (WHR), waist circumference (WC), and physical activity (PA) with gray matter cerebral blood flow (CBF
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.