Evidence map›Paper›PMID 34022420›Full record

ArticleJournal of biomedical informatics2021

Population stratification enables modeling effects of reopening policies on mortality and hospitalization rates.

Tongtong Huang, Yan Chu, Shayan Shams, Yejin Kim, Ananth V Annapragada, Devika Subramanian, Ioannis Kakadiaris, Assaf Gottlieb, Xiaoqian Jiang

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Machine Learning and COVID-19: Lessons from SARS-CoV-2.Advances in experimental medicine and biology · 2023
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tongtong HuangSchool of Biomedical Informatics, UTHealth, Houston, TX, United States. Electronic address: Tongtong.Huang@uth.tmc.edu.
Yan ChuSchool of Biomedical Informatics, UTHealth, Houston, TX, United States.
Shayan ShamsSchool of Biomedical Informatics, UTHealth, Houston, TX, United States.
Yejin KimSchool of Biomedical Informatics, UTHealth, Houston, TX, United States.
Ananth V AnnapragadaDepartment of Pediatric Radiology, Texas Children's Hospital, Houston, TX, United States.
Devika SubramanianDepartment of Computer Science & Electrical and Computer Engineering, Rice University, Houston, TX, United States.
Ioannis KakadiarisDepartment of Computer Science, Electrical & Computer Engineering, and Biomedical Engineering University of Houston, Houston, TX, United States.
Assaf GottliebSchool of Biomedical Informatics, UTHealth, Houston, TX, United States.
Xiaoqian JiangSchool of Biomedical Informatics, UTHealth, Houston, TX, United States.

Funding

The PreVAIL-kIds Common ProtocolR33HD105593 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E, ANNAPRAGADA, ANANTH V · 2023 to 2023
$6.3M
Finding Combinatorial Drug Repositioning Therapy For Alzheimer'S Disease And Related DementiasR01AG066749 · NIA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI JIANG, XIAOQIAN, ZHENG, WENJIN JIM · 2020 to 2024
$4.4M
AICORE-kids: Artificial Intelligence COVID-19 Risk AssEssment for kidsR61HD105593 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI ALLEN, CARL E, ANNAPRAGADA, ANANTH V · 2021 to 2022
$1.6M
NIA NIH HHS R01 AG066749NICHD NIH HHS R33 HD105593NICHD NIH HHS R61 HD105593
6 · The paper itself

Abstract

objectiveStudy the impact of local policies on near-future hospitalization and mortality rates. MATERIALS AND

methodsWe introduce a novel risk-stratified SIR-HCD model that introduces new variables to model the dynamics of low-contact (e.g., work from home) and high-contact (e.g., work on-site) subpopulations while sharing parameters to control their respective R

resultsWe evaluated our model's forecasting accuracy in Harris County, TX (the most populated county in the Greater Houston area) during Phase-I and Phase-II reopening. Not only does our model outperform other competing models, but it also supports counterfactual analysis to simulate the impact of future policies in a local setting, which is unique among existing approaches. DISCUSSION: Mortality and hospitalization rates are significantly impacted by local quarantine and reopening policies. Existing models do not directly account for the effect of these policies on infection, hospitalization, and death rates in an explicit and explainable manner. Our work is an attempt to improve prediction of these trends by incorporating this information into the model, thus supporting decision-making.

conclusionOur work is a timely effort to attempt to model the dynamics of pandemics under the influence of local policies.

Indexed as

COVID-19HospitalizationHumansPandemicsPolicySARS-CoV-2United StatesCOVID-19Epidemic forecasting modelReopening policyRisk stratificationSIRSIR-HCD

Identifiers

PMID34022420
PMCPMC8555375

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.