Evidence map›Paper›PMID 34022067›Full record

ArticlePacing and clinical electrophysiology : PACE2021

Impact of the COVID-19 lockdown on the arrhythmic burden of patients with implantable cardioverter-defibrillators.

Biagio Sassone, Santo Virzì, Matteo Bertini, Giovanni Pasanisi, Lamberto Manzoli, Jonathan Myers, Giovanni Grazzi, Daniele Muser

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Pacing and clinical electrophysiology : PACE, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Ventricular arrhythmia burden in ICD patients during the second wave of the COVID-19 pandemic.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Biagio SassoneDepartment of Translational Medicine, University of Ferrara, Ferrara, Italy.ORCID 0000-0002-9028-7169
Santo VirzìDepartment of Emergency, Division of Cardiology, SS.ma Annunziata Hospital, Ferrara, Italy.
Matteo BertiniCardiological Centre, Department of Translational Medicine, University of Ferrara, Ferrara, Italy.
Giovanni PasanisiDepartment of Emergency, Division of Cardiology, Delta Hospital, Ferrara, Italy.
Lamberto ManzoliDepartment of Medical Sciences, University of Ferrara, Ferrara, Italy.
Jonathan MyersDivision of Cardiology, VA Palo Alto, Palo Alto, California, USA.
Giovanni GrazziCentre for Exercise Science and Sport, University of Ferrara, Ferrara, Italy.
Daniele MuserCardiac Electrophysiology, Cardiovascular Division, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-4323-5988
University of Ferrara · ITOspedale SS. Annunziata · ITUniversity of Udine · ITVA Palo Alto Health Care System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Italy, a nationwide full lockdown was declared between March and May 2020 to hinder the novel coronavirus disease 2019 (COVID-19) pandemic. The potential individual health effects of long-term isolation are largely unknown. The current study investigated the arrhythmic consequences of the COVID-19 lockdown in patients with defibrillators (ICDs) living in the province of Ferrara, Italy.

methodsBoth the arrhythmias and the delivered ICD therapies as notified by the devices were prospectively collected during the lockdown period (P1) and compared to those occurred during the 10 weeks before the lockdown began (P2) and during the same period in 2019 (P3). Changes in outcome over the three study periods were evaluated for significance using McNemar's test.

resultsA total of 413 patients were included in the analysis. No differences were found concerning either arrhythmias or shocks or anti-tachycardia pacing. Only the number of patients experiencing non-sustained ventricular tachycardias (NSVTs) during P1 significantly decreased as compared to P2 (p = 0.026) and P3 (p = 0.009). The subgroup analysis showed a significant decrease in NSVTs during P1 for men (vs. P2, p = 0.014; vs. P3, p = 0.040) and younger patients (vs. P2, p = 0.002; vs. P3, p = 0.040) and for ischemic etiology (vs. P2, p = 0.003). No arrhythmic deaths occurred during P1.

conclusionsThe complete nationwide lockdown, as declared by the Italian government during the first COVID-19 pandemic peak, did not impact on the incidence of arrhythmias in an urban cohort of patients with ICDs.

Indexed as

Defibrillators, ImplantableAgedArrhythmias, CardiacCOVID-19FemaleHumansItalyMalePandemicsPhysical DistancingPneumonia, ViralProspective StudiesSARS-CoV-2arrhythmiaCOVID-19defibrillatorlockdown

Identifiers

PMID34022067
PMCPMC8207039
OpenAlexW3164862996

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.