Evidence map›Paper›PMID 34021873›Full record

ArticleBiological trace element research2022

Health Hazard Assessment Due to Slimming Medicinal Plant Intake.

Laís Caroline Werdemberg Dos Santos, Daniela Granja Arakaki, Elaine Silva de Pádua Melo, Valter Aragão Nascimento

Abstract read
PubMed Publisher
In one paragraph

Article in Biological trace element research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  4. Article
  5. Article
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  8. ICP-OES assessment of trace and toxic elements in Ziziphora clinopodioides Lam. from Iran by chemometric approaches.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2022
    Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laís Caroline Werdemberg Dos SantosGEBABS - Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health, Federal University of Mato Grosso do Sul, Campo Grande, 79070-900, Brazil.ORCID https://orcid.org/0000-0002-2876-8260
Daniela Granja ArakakiGEBABS - Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health, Federal University of Mato Grosso do Sul, Campo Grande, 79070-900, Brazil.ORCID https://orcid.org/0000-0002-2066-7908
Elaine Silva de Pádua MeloGEBABS - Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health, Federal University of Mato Grosso do Sul, Campo Grande, 79070-900, Brazil.ORCID https://orcid.org/0000-0002-4766-7334
Valter Aragão NascimentoGEBABS - Group of Spectroscopy and Bioinformatics Applied Biodiversity and Health, Federal University of Mato Grosso do Sul, Campo Grande, 79070-900, Brazil. aragao60@hotmail.com.ORCID http://orcid.org/0000-0002-9020-8002
Universidade Federal de Mato Grosso do Sul · BR

Funding

CAPES 001
6 · The paper itself

Abstract

According to the World Health Organization (WHO), about 80% of people rely on medicinal plants for their primary health needs. Traditional medicine's principal benefits are their vast population knowledge, low severe adverse effects rate, low cost, and the lack of a medical prescription to use them. While obesity has become a global health issue, an increase in finding cheap and fast ways to lose weight escalates medicinal herbs' use for this purpose, both in dietary supplements or in teas. At the same time that Brazil aims to expand traditional medicine, reports regarding toxicology and poisoning put natural products' safety in check. Plants can accumulate heavy metals and metalloids leading to health risks; however, there is a lack of information on that matter, possibly due to a lack of international standardization regarding elemental contamination - this study aimed to determine metal and metalloid concentrations in slimming medicinal plants and their respective teas and evaluate their safety consumption. Metal and metalloid content were determined by inductively coupled plasma optical emission spectrometry (ICP OES). All plants and teas were within the set limits for tolerable upper intake level (UL), provisional tolerable daily maximum intake (PTDMI), and provisional tolerable weekly intake (PTWI). The hazard quotient index (HQ) was above 1 for almost all plants, and the Hibiscus sabdariffa tea regarding aluminum content. The arsenic level was above the Brazilian Pharmacopeia limit in natura plants demonstrating risk in their consumption. Some herbs also presented detection for elements with no safety limits set, such as lead, cadmium, and arsenic, which could mark as a red flag for consumption once their security intake is not precise yet.

Indexed as

ArsenicMetals, HeavyPlants, MedicinalCadmiumFood ContaminationHumansMedicine, TraditionalRisk AssessmentArsenicCadmiumMetals, HeavyElemental contentHeavy metalsMedicinal plantsSafety

Identifiers

PMID34021873
OpenAlexW3161096598

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.