Evidence map›Paper›PMID 34021466›Full record

ArticleSleep & breathing = Schlaf & Atmung2022

The effect of continuous positive airway pressure treatment on hypertensive disorder in pregnant women with obstructive sleep apnea.

Dragan Stajić, Djordje Ilić, Jelena Vuković, Branislava Baturan, Aleksandra Ilić, Aleksandra Milovančev

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Bioactivity Profiling ofPharmaceuticals (Basel, Switzerland) · 2024
    Article
  8. Review
  9. International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023
    Review
  10. Article
  11. Article
  12. Obstructive sleep apnea in pregnant women.International anesthesiology clinics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Dragan StajićFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia.
Djordje IlićFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia.
Jelena VukovićFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia.
Branislava BaturanFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia.
Aleksandra IlićFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia.
Aleksandra MilovančevFaculty of Medicine, University of Novi Sad, Hajduk Veljkova 3 21 000, Novi Sad, Serbia. aleksandra.milovancev@mf.uns.ac.rs.ORCID 0000-0002-4398-8093
University of Novi Sad · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeOur study aimed to determine the effect of continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea (OSA) on the incidence and severity of hypertensive syndrome in pregnancy.

methodsThe study included women with high-risk pregnancies and the Epworth Sleepiness Scale score ≥ of 10. Polygraphic testing was done between 18 and 20 weeks. Participants were divided into three groups: pregnant women with OSA starting treatment with CPAP for 4 weeks between 24 and 28 gestational weeks, women with OSA treated conservatively, and women without OSA as the control group. Participants were followed up regularly for 4 weeks until the delivery and 1 week after for the occurrence of hypertensive syndrome and other maternal complications.

resultsAmong the 110 women enrolled in the study, the prevalence of hypertensive syndrome in 41 pregnant women with OSA treated conservatively was 39%, 50 women with OSA treated with CPAP 26%, and 19 women in the control group 21%, p = 0.1. The group treated with CPAP when compared with the conservatively treated group had a significantly lower incidence of severe forms of hypertensive syndrome (8% vs. 24%, p = 0.02.), and after 1 month of treatment had higher night oxygen saturation (92%, vs. 87%, p = 0.003) and lower Epworth Sleepiness Scale score (respectively, 4.2 ± 2.3 vs. 9.4 ± 4.1, p < 0001). The respiratory event index was significantly associated with hypertension severity (patients with preeclampsia 9.5 ± 4.9 vs. without hypertension 6.9 ± 4.5, p = 0.04).

conclusionCPAP therapy significantly reduced the incidence of severe forms of hypertensive syndrome in pregnant women with OSA.

Indexed as

Continuous Positive Airway PressureAdultFemaleHumansHypertension, Pregnancy-InducedIncidencePregnancySeverity of Illness IndexSleep Apnea, ObstructiveBlood pressurePreeclampsiaPregnancySleep apnea

Identifiers

PMID34021466
OpenAlexW3163849174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.