Evidence map›Paper›PMID 34021369›Full record

ArticleAnalytical and bioanalytical chemistry2021

Determination of minimal sequence for zearalenone aptamer by computational docking and application on an indirect competitive electrochemical aptasensor.

Farah Asilah Azri, Jinap Selamat, Rashidah Sukor, Nor Azah Yusof, Nurul Hanun Ahmad Raston, Shimaa Eissa, Mohammed Zourob, Raja Chinnappan

Abstract read
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In one paragraph

Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Farah Asilah AzriFood Safety and Food Integrity, Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia.
Jinap SelamatFood Safety and Food Integrity, Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia. sjinap@gmail.com.ORCID http://orcid.org/0000-0002-8369-9536
Rashidah SukorFood Safety and Food Integrity, Institute of Tropical Agriculture and Food Security, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia.
Nor Azah YusofDepartment of Chemistry, Faculty of Science, Universiti Putra Malaysia, UPM, 43400, Serdang, Selangor, Malaysia.
Nurul Hanun Ahmad RastonSchool of Bioscience and Biotechnology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, UKM, 43600, Bangi, Selangor, Malaysia.
Shimaa EissaDepartment of Chemistry, Alfaisal University, Al Zahrawi Street, Al Maather, AlTakhassusi, Riyadh, 11533, Saudi Arabia.
Mohammed ZourobDepartment of Chemistry, Alfaisal University, Al Zahrawi Street, Al Maather, AlTakhassusi, Riyadh, 11533, Saudi Arabia.
Raja ChinnappanDepartment of Chemistry, Alfaisal University, Al Zahrawi Street, Al Maather, AlTakhassusi, Riyadh, 11533, Saudi Arabia.
Universiti Putra Malaysia · MYAlfaisal University · SANational University of Malaysia · MY

Funding

Malaysian Ministry of Higher Education High Impact Centre of Excellence (HICoE) grant schUniversiti Putra Malaysia Graduate Research Fellowship (GRF)
6 · The paper itself

Abstract

Aptamers are short single-stranded oligonucleotides (either DNA or RNA) that can fold into well-defined three-dimensional (3D) spatial structures which enable them to capture their specific target by complementary shape interactions. Aptamers are selected from large random libraries through the SELEX process and only a small fraction of the sequence is involved in direct docking with the target. In this paper, we describe the possible truncation variants of zearalenone (ZEA) aptamer which might be an effective binding region for the target. The originally selected zearalenone (ZEA) aptamer was 80-mer in length and shown to bind the target with a high affinity (K

Indexed as

Aptamers, NucleotideBase SequenceBiosensing TechniquesCircular DichroismDielectric SpectroscopyElectrochemical TechniquesLimit of DetectionMolecular Docking SimulationZearalenoneAptamers, NucleotideZearalenoneAptamersComputational dockingTruncationZearalenone

Identifiers

PMID34021369
OpenAlexW3163694798

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.