ArticleSkeletal radiology2021
Correlation between Hounsfield unit derived from head, thorax, abdomen, spine and pelvis CT and t-scores from DXA.
Article in Skeletal radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- CT Hounsfield Unit Measurements Around the Hip and Their Utility for Opportunistic Screening: A Systematic Review.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026Pooled it
- Opportunistic CT-based osteoporosis screening of the hip: a systematic review of diagnostic accuracy.Archives of orthopaedic and trauma surgery · 2025Pooled it
- Pooled it
- Article
- Osteoporosis screening and major osteoporotic fracture prediction by cranial computed tomography-derived Hounsfield units: a multi-center study on opportunistic osteoporosis screening.Annals of medicine · 2025Article
- Can Hounsfield Unit Evaluation of Preoperative CT Scans Predict Surgeon's Preference of Cementless Fixation in Total Knee Arthroplasty?Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2025Article
- Gradient-enhanced neural network and extreme gradient boosting modeling for the prediction of the 3D bone mineral density distribution from 2D-DXA scans.Osteoporosis and sarcopenia · 2025Article
- Application of deformity principles in the management of spinal neoplasms: A Primer.North American Spine Society journal · 2025Article
- Regions of interest in opportunistic computed tomography-based screening for osteoporosis: impact on short-term in vivo precision.Skeletal radiology · 2025Article
- Hounsfield unit correlates with intervertebral disc degeneration in premenopausal and menopausal women: a radiological study.Journal of orthopaedic surgery and research · 2025Article
- Opportunistic screening for osteoporosis using routine clinical care computed tomography brain studies.Skeletal radiology · 2025Article
- Feasibility study in quantitative identification of fresh and old osteoporotic vertebral compression fracture by vertebral CT value and CT value difference.BMC musculoskeletal disorders · 2024Article
- The influence of proliferative tissue on Hounsfield unit and its correlation with BMD in middle-aged and elderly patients with lumbar degenerative diseases.Journal of orthopaedic surgery and research · 2024Article
- Hounsfield units in assessing bone mineral density in ankylosing spondylitis patients with cervical fracture-dislocation.World journal of clinical cases · 2024Article
- Vertebral HU value and the pectoral muscle index based on chest CT can be used to opportunistically screen for osteoporosis.Journal of orthopaedic surgery and research · 2024Article
- The Suitable Population for Opportunistic Low Bone Mineral Density Screening Using Computed Tomography.Clinical interventions in aging · 2024Article
- Feasibility of diagnosing osteoporosis using routine computed tomography scans for hip fractures: Correlation with histopathological diagnosis of head and neck regions.Acta orthopaedica et traumatologica turcica · 2023Article
- CT and MR for bone mineral density and trabecular bone score assessment in osteoporosis evaluation.Scientific reports · 2023Article
- Article
- Routine chest CT combined with the osteoporosis self-assessment tool for Asians (OSTA): a screening tool for patients with osteoporosis.Skeletal radiology · 2023Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesCT examination can potentially be utilised for early detection of bone density changes with no additional procedure and radiation dose. We hypothesise that the Hounsfield unit (HU) measured from CT images is correlated to the t-scores derived from dual energy X-ray absorptiometry (DXA) in multiple anatomic regions. MATERIALS &
methodsData were obtained retrospectively from all patients who underwent both CT examinations - brain (frontal bone), thorax (T7), abdomen (L3), spine (T7 & L3) or pelvis (left hip) - and DXA between 2014 and 2018 in our centre. To ensure comparability, the period between CT and DXA studies must not exceed one year. Correlations between HU values and t-scores were calculated using Pearson's correlation. Receiver operating characteristic (ROC) curves were generated, and the area under the curve (AUC) was used to determine threshold HU values for predicting osteoporosis.
resultsThe inclusion criteria were met by 1043 CT examinations (136 head, 537 thorax, 159 lumbar and 151 left hip). The left hip consistently provided the most robust correlations (r = 0.664-0.708, p < 0.001) and the best AUC (0.875-0.893). Meanwhile, thorax T7 and lumbar L3 showed average correlations (range of r values is 0.497-0.679, p < 0.001, AUC range = 0.680-0.783, 95% CI 0.561-0.922, all p < 0.02) and moderate AUC (0.680-0.783). Frontal bone shows low correlation and weak AUC with r < 0.5, AUC = 0.538-0.655, all p > 0.05.
conclusionHU values derived from the hip, T7 and L3 provided a good to moderate correlation to t-scores with a good prediction for osteoporosis. The suggested optimal thresholds may be used in clinical settings after external validations are performed.
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