Evidence map›Paper›PMID 34021352›Full record

ArticleJournal of the National Cancer Institute2021

Association of Medicaid Expansion With Cancer Stage and Disparities in Newly Diagnosed Young Adults.

Xu Ji, Sharon M Castellino, Ann C Mertens, Jingxuan Zhao, Leticia Nogueira, Ahmedin Jemal, K Robin Yabroff, Xuesong Han

Abstract read
In one paragraph

Article in Journal of the National Cancer Institute, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Observational
  2. Disparities in Rural-Urban Cancer Care Outcomes among Pediatric, Adolescent, and Young Adult Populations: A Comprehensive Narrative Review.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Impact of Medicaid expansion on stage of diagnosis of lung cancer for rural and urban patients in New Hampshire.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  9. Article
  10. Article
  11. Association Between State Medicaid Policies and Accrual of Black or Hispanic Patients to Cancer Clinical Trials.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Access to Care for Adolescents and Young Adults With Cancer in the United States: State of the Literature.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2024
    Review
  16. Article
  17. Article
  18. Survival in Young Adults With Cancer Is Associated With Medicaid Expansion Through the Affordable Care Act.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xu JiDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-3025-3984
Sharon M CastellinoDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.
Ann C MertensDepartment of Pediatrics, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0003-0989-0962
Jingxuan ZhaoSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0002-2733-2000
Leticia NogueiraSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0001-6990-3660
Ahmedin JemalSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0002-0000-4111
K Robin YabroffSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0003-0644-5572
Xuesong HanSurveillance and Health Equity Science, American Cancer Society, Atlanta, GA, USA.ORCID 0000-0001-7159-7949

Funding

Understanding the impact of the Affordable Care Act on cancer treatment and outcomes for adolescents and young adults (AYA)R03CA259665 · NCI · EMORY UNIVERSITY · PI CASTELLINO, SHARON MARIE, JI, XU · 2021 to 2022
$158k
NCI NIH HHS R03 CA259665
6 · The paper itself

Abstract

backgroundYoung adults (YAs) experience higher uninsurance rates and more advanced stage at cancer diagnosis than older counterparts. We examined the association of the Affordable Care Act Medicaid expansion with insurance coverage and stage at diagnosis among YAs newly diagnosed with cancer.

methodsUsing the National Cancer Database, we identified 309 413 YAs aged 18-39 years who received a first cancer diagnosis in 2011-2016. Outcomes included percentages of YAs without health insurance at diagnosis, with stage I (early-stage) diagnoses, and with stage IV (advanced-stage) diagnoses. We conducted difference-in-difference (DD) analyses to examine outcomes before and after states implemented Medicaid expansion compared with nonexpansion states. All statistical tests were 2-sided.

resultsThe percentage of uninsured YAs decreased more in expansion than nonexpansion states (adjusted DD = -1.0 percentage points [ppt], 95% confidence interval [CI] = -1.4 to -0.7 ppt, P < .001). The overall percentage of stage I diagnoses increased (adjusted DD = 1.4 ppt, 95% CI = 0.6 to 2.2 ppt, P < .001) in expansion compared with nonexpansion states, with greater improvement among YAs in rural areas (adjusted DD = 7.2 ppt, 95% CI = 0.2 to 14.3 ppt, P = .045) than metropolitan areas (adjusted DD = 1.3 ppt, 95% CI = 0.4 to 2.2 ppt, P = .004) and among non-Hispanic Black patients (adjusted DD = 2.2 ppt, 95% CI = -0.03 to 4.4 ppt, P = .05) than non-Hispanic White patients (adjusted DD = 1.4 ppt, 95% CI = 0.4 to 2.3 ppt, P = .008). Despite the non-statistically significant change in stage IV diagnoses overall, the percentage declined more (adjusted DD = -1.2 ppt, 95% CI = -2.2 to -0.2 ppt, P = .02) among melanoma patients in expansion relative to nonexpansion states.

conclusionsWe provide the first evidence, to our knowledge, on the association of Medicaid expansion with shifts to early-stage cancer at diagnosis and a narrowing of rural-urban and Black-White disparities in YA cancer patients.

Indexed as

MedicaidTesticular NeoplasmsHumansInsurance CoverageMaleMedically UninsuredPatient Protection and Affordable Care ActUnited StatesYoung Adult

Identifiers

PMID34021352
PMCPMC9989840

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.