Evidence map›Paper›PMID 34021177›Full record

ArticleScientific reports2021

Fluorescence Fluctuation Spectroscopy enables quantification of potassium channel subunit dynamics and stoichiometry.

Giulia Tedeschi, Lorenzo Scipioni, Maria Papanikolaou, Geoffrey W Abbott, Michelle A Digman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Giulia Tedeschi *Department of Biomedical Engineering, Laboratory for Fluorescence Dynamics, University of California Irvine, Irvine, CA, 92697, USA.
Lorenzo Scipioni *Department of Biomedical Engineering, Laboratory for Fluorescence Dynamics, University of California Irvine, Irvine, CA, 92697, USA.
Maria PapanikolaouDepartment of Physiology and Biophysics, Bioelectricity Laboratory, School of Medicine, University of California Irvine, Irvine, CA, 92697, USA.
Geoffrey W AbbottDepartment of Physiology and Biophysics, Bioelectricity Laboratory, School of Medicine, University of California Irvine, Irvine, CA, 92697, USA. abbottg@uci.edu.
Michelle A DigmanDepartment of Biomedical Engineering, Laboratory for Fluorescence Dynamics, University of California Irvine, Irvine, CA, 92697, USA. mdigman@uci.edu.
University of California, Irvine · USFluor (United States) · US

Funding

TRD4: Phasor analysisP41GM103540 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GRATTON, ENRICO · 2012 to 2020
$12.5M
Real-time potassium channel subunit dynamicsR21DC015736 · NIDCD · UNIVERSITY OF CALIFORNIA-IRVINE · PI ABBOTT, GEOFFREY W · 2016 to 2017
$425k
NIDCD NIH HHS R21 DC015736NIGMS NIH HHS P41 GM103540
6 · The paper itself

Abstract

Voltage-gated potassium (Kv) channels are a family of membrane proteins that facilitate K

Indexed as

Protein Interaction Domains and MotifsSpectrum AnalysisAction PotentialsAnimalsCHO CellsCricetulusHumansIon Channel GatingModels, MolecularMolecular ConformationPatch-Clamp TechniquesPotassium ChannelsProtein BindingStructure-Activity RelationshipPotassium Channels

Identifiers

PMID34021177
PMCPMC8140153
OpenAlexW3111041204

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.