Evidence map›Paper›PMID 34021042›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

The Motor Basis for Misophonia.

Sukhbinder Kumar, Pradeep Dheerendra, Mercede Erfanian, Ester Benzaquén, William Sedley, Phillip E Gander, Meher Lad, Doris E Bamiou, Timothy D Griffiths

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06333925 (Using Neurostimulation to Accelerate Change in Misophonia), which is not on this map. Cited by 41 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06333925 nacompletednot on this mapstarted 2024, after this paper: background citation

Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study

TypeinterventionalSponsorDuke UniversityRan2024 to 2026Enrolled59ConditionsMisophonia, Emotion Dysregulation, Sensory Processing Disorder, Auditory Over ResponsivityArmsHigh Frequency Repetitive Transcranial Magnetic Stimulation (HF rTMS), Sham Repetitive Transcranial Magnetic Stimulation (sham- rTMS), Cognitive Restructuring
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Misophonia: A Systematic Review of Current and Future Trends in This Emerging Clinical Field.International journal of environmental research and public health · 2022
    Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Misophonia symptom severity is linked to impaired flexibility and heightened rumination.British journal of psychology (London, England : 1953) · 2026
    Article
  7. Misophonia Symptoms in Autistic Adults.Journal of autism and developmental disorders · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. A social cognition perspective on misophonia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  18. Brain circuits in autonomous sensory meridian response and related phenomena.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  19. Misophonia reactions in the general population are correlated with strong emotional reactions to other everyday sensory-emotional experiences.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Sukhbinder KumarBiosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom Sukhbinder.kumar@ncl.ac.uk.
Pradeep DheerendraBiosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom.ORCID https://orcid.org/0000-0002-1575-154X
Mercede ErfanianUCL Institute for Environmental Design and Engineering, The Bartlett, University College London, WC1H 0NN, United Kingdom.
Ester BenzaquénBiosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom.
William SedleyTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH.
Phillip E GanderDepartment of Neurosurgery, University of Iowa, Iowa City, Iowa 52242.
Meher LadTranslational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH.
Doris E BamiouUCL Ear Institute, London, WC1X 8EE, United Kingdom.
Timothy D GriffithsBiosciences Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, United Kingdom.
Newcastle University · GBClinical Research Institute · USUniversity of Iowa · USUniversity College Hospital · GBUniversity College London · GB

Funding

Medical Research Council MR/T032553/1Medical Research Council MR/V006568/1Wellcome Trust
6 · The paper itself

Abstract

Misophonia is a common disorder characterized by the experience of strong negative emotions of anger and anxiety in response to certain everyday sounds, such as those generated by other people eating, drinking, and breathing. The commonplace nature of these "trigger" sounds makes misophonia a devastating disorder for sufferers and their families. How such innocuous sounds trigger this response is unknown. Since most trigger sounds are generated by orofacial movements (e.g., chewing) in others, we hypothesized that the mirror neuron system related to orofacial movements could underlie misophonia. We analyzed resting state fMRI (rs-fMRI) connectivity (

Indexed as

NoiseAcoustic StimulationAdultAffective SymptomsBrain MappingCerebral CortexFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedMirror NeuronsNeural PathwaysauditoryfMRImirror neuronsmisophoniamotor systemresting state connectivity

Identifiers

PMID34021042
PMCPMC8244967
OpenAlexW3161514681

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.