Evidence map›Paper›PMID 34021010›Full record

ArticleCMAJ open

Use of HIV pre-exposure prophylaxis among urban Canadian gay, bisexual and other men who have sex with men: a cross-sectional analysis of the Engage cohort study.

Joseph Cox, Herak Apelian, Erica E M Moodie, Marc Messier-Peet, Trevor A Hart, Daniel Grace, David M Moore, Nathan J Lachowsky, Heather L Armstrong, Jody Jollimore and 10 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in CMAJ open. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Canadian guideline on HIV pre- and postexposure prophylaxis: 2025 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
  2. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2025
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Joseph CoxDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que. joseph.cox@mcgill.ca.
Herak ApelianDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Erica E M MoodieDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Marc Messier-PeetDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Trevor A HartDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Daniel GraceDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
David M MooreDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Nathan J LachowskyDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Heather L ArmstrongDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Jody JollimoreDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Shayna Skakoon-SparlingDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Ricky RodriguesDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Darrell H S TanDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Mathieu Maheu-GirouxDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Syed W NoorDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Bertrand LebouchéDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Cecile TremblayDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Gbolahan OlarewajuDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Gilles LambertDepartment of Epidemiology, Biostatistics & Occupational Health (Cox, Moodie, Maheu-Giroux), McGill University; Direction régionale de santé publique, Centre intégré universitaire de santé et de services sociaux Centre-Sud-de-l'Ile-de-Montréal (Cox, Apelian, Messier-Peet, Lambert); Research Institute of the McGill University Health Centre (Apelian, Messier-Peet), Montréal, Que.; Department of Psychology (Hart, Skakoon-Sparling, Rodrigues, Noor), Ryerson University; Dalla Lana School of Public Health (Grace), University of Toronto, Toronto, Ont.; British Columbia Centre for Excellence in HIV/AIDS (Moore, Armstrong, Olarewaju); Faculty of Medicine (Moore), University of British Columbia, Vancouver, BC; School of Public Health & Social Policy (Lachowsky), Faculty of Human & Social Development, University of Victoria, Victoria, BC; Department of Psychology (Armstrong), University of Southampton, Southampton, UK; Community-Based Research Centre (Jollimore), Vancouver, BC; Division of Infectious Diseases (Tan), St. Michael's Hospital; Department of Medicine (Tan), University of Toronto, Toronto, Ont.; Department of Family Medicine (Lebouché), Faculty of Medicine, McGill University; Centre for Outcomes Research and Evaluation (Lebouché), Research Institute of the McGill University Health Centre; Centre de recherche du centre hospitalier de l'Université de Montréal (Tremblay); Institut national de santé publique du Québec (Lambert), Montréal, Que.
Engage Study Team

Funding

CIHR CTN300CIHR FDN=143342CIHR PJT-153139CIHR TE2-138299
6 · The paper itself

Abstract

backgroundIn Canada, gay, bisexual and other men who have sex with men (GBM) are disproportionately affected by HIV. Our objective was to describe access to HIV pre-exposure prophylaxis (PrEP) and identify factors associated with not using PrEP among self-reported HIV-negative or HIV-unknown GBM.

methodsThis was a cross-sectional analysis of the Engage study cohort. Between 2017 and 2019, sexually active GBM aged 16 years or more in Montréal, Toronto and Vancouver were recruited via respondent-driven sampling (RDS). Participation included testing for HIV and sexually transmitted and blood-borne infections, and completion of a questionnaire. We examined PrEP access using a health care services model and fit RDS-adjusted logistic regressions to determine correlates of not using PrEP among those for whom PrEP was clinically recommended and who were aware of the intervention.

resultsA total of 2449 GBM were recruited, of whom 2008 were HIV-negative or HIV-unknown; 1159 (511 in Montréal, 247 in Toronto and 401 in Vancouver) met clinical recommendations for PrEP. Of the 1159, 1100 were aware of PrEP (RDS-adjusted proportion: Montréal 84.6%, Toronto 94.2%, Vancouver 92.7%), 678 had felt the need for PrEP in the previous 6 months (RDS-adjusted proportion: Montréal 39.2%, Toronto 56.1%, Vancouver 49.0%), 406 had tried to access PrEP in the previous 6 months (RDS-adjusted proportion: Montréal 20.6%, Toronto 33.2%, Vancouver 29.6%) and 319 had used PrEP in the previous 6 months (RDS-adjusted proportion: Montréal 14.5%, Toronto 21.6%, Vancouver 21.8%). Not using PrEP was associated with several factors, including not feeling at high enough risk, viewing PrEP as not completely effective, not having a primary care provider and lacking medication insurance.

interpretationAlthough half of GBM met clinical recommendations for PrEP, less than a quarter of them reported use. Despite high levels of awareness, a programmatic response that addresses PrEP-related perceptions and health care system barriers is needed to scale up PrEP access among GBM in Canada.

Indexed as

Drug MonitoringMedication AdherencePre-Exposure ProphylaxisSexual and Gender MinoritiesAdultAttitude to HealthCanadaHealth Knowledge, Attitudes, PracticeHealth Services AccessibilityHealth Services Needs and DemandHIV InfectionsHumansMaleQualitative ResearchRisk-Taking

Identifiers

PMID34021010
PMCPMC8177951

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.