ArticleBMC complementary medicine and therapies2021
Antifungal and anti-biofilm activity of a new Spanish extract of propolis against Candida glabrata.
Article in BMC complementary medicine and therapies, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 25 citations in OpenAlex.
- Characterization of Heterotrigona itama Propolis Extracts: Phytochemicals and Thermal Insights.Chemistry & biodiversity · 2026Article
- Natural product based approaches to overcomeFrontiers in antibiotics · 2026Review
- Antibacterial, Antifungal, and Wound-Healing Activities and Chemical Characterization of Propolis fromMolecules (Basel, Switzerland) · 2025Article
- Biofilm inhibition of multidrug-resistant Pseudomonas aeruginosa using green-synthesized silver nanoparticles and colistin.Scientific reports · 2025Article
- Antibiofilm sustainable strategies: pomegranate extract from agri-food waste as a natural antifungal against emergingFrontiers in microbiology · 2025Article
- Anti-Biofilm Perspectives of Propolis againstBiomolecules · 2024Article
- Pathogenic Biofilm Removal Potential of Wild-TypePathogens (Basel, Switzerland) · 2023Article
- Antifungal Activity of Mexican Propolis on Clinical Isolates ofMolecules (Basel, Switzerland) · 2022Article
- Antibiofilm and Anti-Quorum Sensing Potential of Cycloartane-Type Triterpene Acids from Cameroonian Grassland Propolis: Phenolic Profile and Antioxidant Activity of Crude Extract.Molecules (Basel, Switzerland) · 2022Article
- Decomposition of Growth Curves into Growth Rate and Acceleration: a Novel Procedure To Monitor Bacterial Growth and the Time-Dependent Effect of Antimicrobials.Applied and environmental microbiology · 2022Article
- Antifungal Properties of Chemically Defined Propolis from Various Geographical Regions.Microorganisms · 2022Review
- Physicochemical characterization andVeterinary world · 2022Article
- Antimicrobial activity of a novel Spanish propolis against planktonic and sessile oral Streptococcus spp.Scientific reports · 2021Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundResistance to traditional antifungal agents is a considerable health problem nowadays, aggravated by infectious processes related to biofilm formation, usually on implantable devices. Therefore, it is necessary to identify new antimicrobial molecules, such as natural products, to develop new therapeutic strategies to prevent and eradicate these infections. One promising product is propolis, a natural resin produced by honeybees with substances from various botanical sources, beeswax and salivary enzymes. The aim of this work was to study the effect of a new Spanish ethanolic extract of propolis (SEEP) on growth, cell surface hydrophobicity, adherence and biofilm formation of Candida glabrata, a yeast capable of achieving high levels of resistance to available anti-fungal agents.
methodsThe antifungal activity of SEEP was evaluated in the planktonic cells of 12 clinical isolates of C. glabrata. The minimum inhibitory concentration (MIC) of propolis was determined by quantifying visible growth inhibition by serial plate dilutions. The minimum fungicide concentration (MFC) was evaluated as the lowest concentration of propolis that produced a 95% decrease in cfu/mL, and is presented as MFC
resultsSEEP had antifungal capacity against C. glabrata isolates, with a MIC
conclusionsThe novel Spanish ethanolic extract of propolis shows antifungal activity against C. glabrata, and decreases biofilm formation. These results suggest its possible use in the control of fungal infections associated with biofilms.
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