ArticleBMC medical imaging2021
Efficacy of ultrasonography and Tc-99m MIBI SPECT/CT in preoperative localization of parathyroid adenomas causing primary hyperthyroidism.
Article in BMC medical imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 22 citations in OpenAlex.
- Quantitative and comparative assessment of Tc-99 m MIBI imaging in parathyroid adenomas: associations with biochemical, morphological, and histopathological.Annals of nuclear medicine · 2026Article
- Clinical outcomes of parathyroidectomy in primary hyperparathyroidism: a 10-year single-center experience with 115 procedures.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Comparative analysis of PTH Washout and 99mTc-MIBI SPECT/CT in presurgical localization for patients with primary hyperparathyroidism.Journal of endocrinological investigation · 2026Article
- Large atypical parathyroid tumor mimicking metastatic papillary thyroid carcinoma: a case report.Journal of medical case reports · 2025Article
- How has the diagnostic approach to parathyroid localization techniques evolved in the past decade? Insights from a single-center experience.Updates in surgery · 2025Observational
- Primary hyperparathyroidism during pregnancy: ultrasound as an accurate preoperative localization imaging modality.Orphanet journal of rare diseases · 2025Article
- The polar vessel sign: insights from CT imaging analysis in Asian Indian primary hyperparathyroidism.Endocrine · 2025Article
- Parathyroid carcinoma as an overlooked etiology of osteoporosis in postmenopausal women: a case report.Frontiers in endocrinology · 2025Article
- Safety evaluation of cinacalcet: Signal mining and analysis of adverse events based on the FAERS database.PloS one · 2025Article
- Precision stratified treatment of primary hyperparathyroidism based on multilevel emerging biomarkers.Frontiers in endocrinology · 2025Review
- Up-to-Date Imaging for Parathyroid Tumor Localization in MEN1 Patients with Primary Hyperparathyroidism: When and Which Ones (A Narrative Pictorial Review).Diagnostics (Basel, Switzerland) · 2024Review
- Large atypical parathyroid tumor - a diagnostic conundrum.Autopsy & case reports · 2024Article
- Clinical, Biochemical, and Sonographic Factors Influencing Performance of Parathormone Washout Measurement vs.Journal of clinical medicine · 2023Article
- Analysis of the successful clinical treatment of 140 patients with parathyroid adenoma: A retrospective study.World journal of clinical cases · 2022Article
- Article
- A Prospective Comparative Study of Using Ultrasonography, 4D-CT and Parathyroid Dual-Phase Scintigraphy with SPECT in Patients with Primary Hyperparathyroidism.Diagnostics (Basel, Switzerland) · 2021Article
- A STEPWISE APPROACH TO LOCALIZATION STUDIES IN PRIMARY HYPERPARATHYROIDISM.Acta endocrinologica (Bucharest, Romania : 2005)Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary hyperparathyroidism (PHPT) results from an excess of parathyroid hormone (PTH) produced from an overactive parathyroid gland. The study aimed to explore the sonographic features of parathyroid adenomas and assess the diagnostic performance of ultrasonography (US) and Tc-99m MIBI SPECT/CT for preoperative localization of parathyroid adenomas.
methodsA total of 107 patients were enrolled in this retrospective study who had PHPT and underwent parathyroidectomy. Of the 107 patients, 97 performed US and Tc-99m MIBI SPECT/CT examinations for preoperative localization of parathyroid nodules. The sensitivity and accuracy of each modality were calculated.
resultsIn this study, residual parathyroid sign and polar vascular sign were identified as characteristic US features of parathyroid adenomas. These manifestations were closely related to the size of the abnormal parathyroid lesions. Among the 108 parathyroid nodules from 97 patients with PHPT, the sensitivity and accuracy of US for locating the parathyroid nodules were significantly higher than those of Tc-99m MIBI SPECT/CT (93.0% vs. 63.0% and 88.0% vs. 63.0% respectively; χ
conclusionsUS shows significantly better sensitivity and accuracy for localization of parathyroid adenomas than Tc-99m MIBI SPECT/CT. However, US combined with Tc-99m MIBI SPECT/CT is of great clinical value in the preoperative localization of parathyroid nodules in patients with PHPT.
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