Evidence map›Paper›PMID 34020592›Full record

ArticleBMC ophthalmology2021

Generalisability through local validation: overcoming barriers due to data disparity in healthcare.

William Greig Mitchell, Edward Christopher Dee, Leo Anthony Celi

Abstract readLetter
In one paragraph

Article in BMC ophthalmology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William Greig MitchellDepartment of Ophthalmology, Massachusetts Eye and Ear Infirmary, Boston, MA, USA.
Edward Christopher DeeHarvard Medical School, Boston, MA, USA.
Leo Anthony CeliHarvard TH Chan School of Public Health, Boston, MA, USA. lceli@mit.edu.ORCID http://orcid.org/0000-0001-6712-6626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we emphasise that recurrent underrepresentation of data-poor regions may inadvertently perpetuate global health inequity.Creating meaningful ML systems is contingent on understanding how, when, and why different ML models work in different settings. While we echo the need for the diversification of ML datasets, such a worthy effort would take time and does not obviate uses of presently available datasets if conclusions are validated and re-calibrated for different groups prior to implementation.The importance of external ML model validation on diverse populations should be highlighted where possible - especially for models built with single-centre data.

Indexed as

Machine LearningMyopiaDelivery of Health CareHumansDisparityHealthcare equityMachine learningOphthalmology

Identifiers

PMID34020592
PMCPMC8138973

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.