Evidence map›Paper›PMID 34020487›Full record

SynthesisThrombosis and haemostasis2022

A Systematic Review of Economic Aspects of Service Interventions to Increase Anticoagulation Use in Atrial Fibrillation.

Nicholas R Jones, William Crawford, Yaling Yang, F D Richard Hobbs, Clare J Taylor, Stavros Petrou

Abstract readSystematic Review
In one paragraph

Synthesis in Thrombosis and haemostasis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Rapid Access Atrial Fibrillation Clinics in Australia - Modelling Outcomes and Cost-Effectiveness.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Predictors of Adherence to Stroke Prevention in the BALKAN-AF Study: A Machine-Learning Approach.TH open : companion journal to thrombosis and haemostasis · 2022
    Article
  7. Atrial fibrillation: NICE 2021 update and the focus on anticoagulation.The British journal of general practice : the journal of the Royal College of General Practitioners · 2022
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nicholas R JonesNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
William CrawfordBarts Health NHS Trust, The Royal London Hospital, London, United Kingdom.
Yaling YangNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
F D Richard HobbsNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Clare J TaylorNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Stavros PetrouNuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.

Funding

Medical Research Council G0501681Wellcome Trust 203921Wellcome Trust 216422
6 · The paper itself

Abstract

objectiveTo systematically identify and appraise existing evidence surrounding economic aspects of anticoagulation service interventions for patients with atrial fibrillation.

methodsWe searched the published and grey literature up to October 2019 to identify relevant economic evidence in any health care setting. A narrative-synthesis approach was taken to summarise evidence by economic design and type of service intervention, with costs expressed in pound sterling and valued at 2017 to 2018 prices.

resultsA total of 13 studies met our inclusion criteria from 1,168 papers originally identified. Categories of interventions included anticoagulation clinics (

conclusionThis review revealed some evidence to support the cost-effectiveness of anticoagulation clinics. However, summative conclusions are constrained by a paucity of economic evidence, a lack of direct comparisons between interventions, and study heterogeneity in terms of intervention, comparator and study year. Further research is urgently needed to inform commissioning and service development. Data from this review can inform future economic evaluations of anticoagulation service interventions.

Indexed as

AnticoagulantsAtrial FibrillationDelivery of Health CareCost-Benefit AnalysisHumansOutcome Assessment, Health CareUnited KingdomAnticoagulants

Identifiers

PMID34020487
PMCPMC7618625

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.