Evidence map›Paper›PMID 34020343›Full record

ArticleJournal of psychosomatic research2021

Associations between adverse childhood experiences and migraine among teenage mothers in Peru.

Cynthia Veronica Siego, Sixto E Sanchez, Maria L Jimenez, Marta B Rondon, Michelle A Williams, B Lee Peterlin, Bizu Gelaye

Open access · greenAbstract read
In one paragraph

Article in Journal of psychosomatic research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Cynthia Veronica SiegoDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Sixto E SanchezUniversidad Peruana de Ciencias Aplicadas, Lima, Peru; Asociación Civil PROESA, Lima, Peru.
Maria L JimenezAsociación Civil PROESA, Lima, Peru.
Marta B RondonDepartment of Medicine, Cayetano Heredia Peruvian University, Lima, Peru.
Michelle A WilliamsDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
B Lee PeterlinDepartment of Neuroscience, Penn Medicine Lancaster General Headache Center, Lancaster, PA, USA.
Bizu GelayeDepartment of Epidemiology, Harvard T. H. Chan School of Public Health, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; The Chester M. Pierce, M.D. Division of Global Psychiatry, Massachusetts General Hospital, Boston, MA, USA. Electronic address: bgelaye@hsph.harvard.edu.
Asociación Civil Impacta Salud y Educación · PEHarvard University · USLancaster General Hospital · USMassachusetts General Hospital · USUniversidad Peruana Cayetano Heredia · PE

Funding

University of Washington MHIRT Training Program GrantT37MD001449 · NIMHD · UNIVERSITY OF WASHINGTON · PI WILLIAMS, MICHELLE A. · 2005 to 2018
$3.5M
NIMHD NIH HHS T37 MD001449
6 · The paper itself

Abstract

objectiveThe objective of this study was to evaluate the association between (1) different types of ACEs and migraine, and (2) the number of ACEs and migraine among adolescent mothers in Lima, Peru.

methodsOur cross-sectional study included 787 adolescent mothers (14- to 18-years of age) in Peru. In-person interviews were conducted postpartum, in hospital, within 2-days of delivery. Nine types of ACEs were assessed, including exposure to three categories of abuse, two categories of neglect, and four categories of household dysfunction. Multivariable logistic regression procedures were used to estimate odds ratios (ORs) and 95% confidence intervals (95% CI) for the association between ACEs and migraine while adjusting for putative confounders.

resultsApproximately 75% of adolescent mothers reported having experienced at least one type of ACE. Adolescent mothers who reported any childhood abuse had 1.49-fold increased odds of migraine (aOR = 1.49; 95% CI 1.03-2.18) compared to those with no history of childhood abuse. Adolescent mothers who reported experiencing household dysfunction had 1.56-fold increase odds of migraine (aOR = 1.56; 95% CI 1.09-2.24). Compared to participants who reported no ACE, those who experienced four or more ACEs had 3.09-fold (aOR = 3.09; 95% CI 1.80-5.40) increased odds of migraine (ptrend < 0.001).

conclusionExposure to ACEs is highly prevalent in adolescent-aged mothers postpartum and is associated with increased odds of migraine. These findings support the importance of screening for ACEs and migraine among adolescent mothers; and the need for providing culturally appropriate, trauma-informed headache care.

Indexed as

Adverse Childhood ExperiencesMigraine DisordersAdolescentAgedChildCross-Sectional StudiesFemaleHumansMothersPeruAdolescent mothersAdverse childhood experiencesChild abuseHousehold dysfunctionMigraine disorders

Identifiers

PMID34020343
PMCPMC8852843
OpenAlexW3157600292

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.