Evidence map›Paper›PMID 34020326›Full record

ArticleClinical neurology and neurosurgery2021

Simultaneous bilateral mechanical thrombectomy in a patient with COVID-19.

Omaditya Khanna, Karim Hafazalla, Fadi Al Saiegh, Rizwan Tahir, Victoria Schunemann, Thana N Theofanis, Nikolaos Mouchtouris, M Reid Gooch, Stavropoula Tjoumakaris, Robert H Rosenwasser and 1 more

Abstract readCase Reports
In one paragraph

Article in Clinical neurology and neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Endovascular treatment strategies for simultaneous bilateral anterior circulation occlusions in acute ischemic stroke: A single-center experience and systematic review of the literature.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Omaditya KhannaDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Karim HafazallaDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Fadi Al SaieghDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Rizwan TahirDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Victoria SchunemannDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Thana N TheofanisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Nikolaos MouchtourisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
M Reid GoochDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Stavropoula TjoumakarisDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Robert H RosenwasserDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA.
Pascal M JabbourDepartment of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, USA. Electronic address: pascal.jabbour@jefferson.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Owing to systemic inflammation and widespread vessel endotheliopathy, SARS-CoV-2 has been shown to confer an increased risk of cryptogenic stroke, particularly in patients without any traditional risk factors. In this report, we present a case of a 67-year-old female who presented with acute stroke from bilateral anterior circulation large vessel occlusions, and was incidentally found to be COVID-positive on routine hospital admission screening. The patient had a large area of penumbra bilaterally, and the decision was made to pursue bilateral simultaneous thrombectomy, with two endovascular neurosurgeons working on each side to achieve a faster time to recanalization. Our study highlights the utility and efficacy of simultaneous bilateral thrombectomy, and this treatment paradigm should be considered for use in patients who present with multifocal large vessel occlusions.

Indexed as

Endovascular ProceduresThrombectomyAgedCarotid Artery ThrombosisCOVID-19FemaleHumansInfarction, Middle Cerebral ArteryStrokeCerebrovascular diseaseCOVID-19InflammationStrokeThrombectomy

Identifiers

PMID34020326
PMCPMC8117485

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.