Evidence map›Paper›PMID 34019808›Full record

ArticleCancer cell2021

A tumor "personality" test to guide therapeutic decision making.

Kathleen E Houlahan, Christina Curtis

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Cancer cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 58% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Linking tumour angiogenesis and tumour immunity.Nature reviews. Immunology · 2026
    Review
  3. Article
  4. Multimodal predictors for precision immunotherapy.Immuno-oncology technology · 2022
    Review
  5. What factors guide treatment selection in mycosis fungoides and Sezary syndrome?Hematology. American Society of Hematology. Education Program · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Kathleen E HoulahanStanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA.
Christina CurtisStanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA; Department of Medicine (Oncology), Stanford University School of Medicine, Stanford, CA, USA; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: cncurtis@stanford.edu.
Stanford Medicine · USStanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this issue of Cancer Cell, Bagaev et al. discover conserved relationships between immune and stroma activity that are prognostic and predictive of response to immunotherapy across cancer types. The authors develop a visualization tool, akin to a tumor personality test, to integrate genomic and microenvironmental profiling and guide therapeutic decision-making.

Indexed as

NeoplasmsDecision MakingHumansImmunotherapyPersonality TestsPrognosis

Identifiers

PMID34019808
OpenAlexW3160794506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.