Evidence map›Paper›PMID 34019629›Full record

ArticleAnesthesiology2021

Pulmonary Aspiration of Gastric Contents: A Closed Claims Analysis.

Mark A Warner, Karen L Meyerhoff, Mary E Warner, Karen L Posner, Linda Stephens, Karen B Domino

5 registry-linked trialsOpen access · bronzeAbstract readEditorial
PubMed Publisher
In one paragraph

Article in Anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
17.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05330351 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Evaluation of Gastric Contents by Ultrasound in Pediatric Trauma Patients Undergoing General Anesthesia

TypeobservationalSponsorChildren's Hospital of PhiladelphiaRan2022 to 2026Enrolled40ConditionsTrauma, Complications, AspirationArmsGastric Ultrasound
NCT05364801 unknown statusnot on this mapstarted 2022, after this paper: background citation

Impact of Anxiety on the Decision-making Process of Anesthesiologists in the Choice of Drugs for Induction of General Anesthesia of Patients With Aspiration Risk Factors

TypeobservationalSponsorCentre Hospitalier Universitaire de BesanconRan2022 to 2024Enrolled500ConditionsAnxiety, Decision Making, General AnesthesiaArmsSurvey
NCT06154486 completednot on this mapstarted 2023, after this paper: background citation

Evaluation of Gastric Content of Volunteers Fasting and Using Semaglutide: an Observational and Cross-sectional Study

TypeobservationalSponsorHospital Israelita Albert EinsteinRan2023 to 2023Enrolled30ConditionsPneumonia, Aspiration, AnesthesiaArmssemaglutide use
NCT06606782 completednot on this map

Evaluation of Incidence of Stomach Fullness in Elective Surgical Patients and Investigation of Associated Factors: Prospective Observational Study

TypeobservationalSponsorRecep Tayyip Erdogan UniversityRan2020 to 2022Enrolled404ConditionsGastric Emptying, Preoperative Care, Preoperative Fasting, Elective Surgical Procedures
NCT06927401 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Evaluate the Detection of Retained Gastric Contents and Assess Safety Using the Flower Capsule Endoscopy in Healthy Individuals and GLP-1 Receptor Agonist Users

TypeinterventionalSponsorAsian Institute of Gastroenterology, IndiaRan2025 to 2025Enrolled36ConditionsEndoscopy, Digestive System, GLP1-R-related DiseaseArmsFlower
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 101 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Observational
  7. Preoperative fasting guidelines: A narrative review.European journal of anaesthesiology and intensive care · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Ultrasound examination of gastric contents in patients undergoing ambulatory surgery.Canadian journal of anaesthesia = Journal canadien d'anesthesie · 2026
    Article
  13. Article
  14. Article
  15. Prevention of bronchopulmonary aspiration in digestive surgery: the impact of training healthcare professionals.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2026
    Article
  16. Focus on POCUS.Ochsner journal · 2026
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 1 institution in 3 countries.

Mark A Warner
Karen L Meyerhoff
Mary E Warner
Karen L Posner
Linda Stephens
Karen B Domino
Mayo Clinic · US

Funding

INSTITUTE FOR TRANSLATIONAL HEALTH SCIENCE (UL1): BPCAUL1RR025014 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$51.5M
NCRR NIH HHS UL1 RR025014
6 · The paper itself

Abstract

backgroundPerioperative pulmonary aspiration of gastric contents has been associated with severe morbidity and death. The primary aim of this study was to identify outcomes and patient and process of care risk factors associated with gastric aspiration claims in the Anesthesia Closed Claims Project. The secondary aim was to assess these claims for appropriateness of care. The hypothesis was that these data could suggest opportunities to reduce either the risk or severity of perioperative pulmonary aspiration.

methodsInclusion criteria were anesthesia malpractice claims in the American Society of Anesthesiologists Closed Claims Project that were associated with surgical, procedural, or obstetric anesthesia care with the year of the aspiration event 2000 to 2014. Claims involving pulmonary aspiration were identified and assessed for patient and process factors that may have contributed to the aspiration event and outcome. The standard of care was assessed for each claim.

resultsAspiration of gastric contents accounted for 115 of the 2,496 (5%) claims in the American Society of Anesthesiologists Closed Claims Project that met inclusion criteria. Death directly related to pulmonary aspiration occurred in 66 of the 115 (57%) aspiration claims. Another 16 of the 115 (14%) claims documented permanent severe injury. Seventy of the 115 (61%) patients who aspirated had either gastrointestinal obstruction or another acute intraabdominal process. Anesthetic management was judged to be substandard in 62 of the 115 (59%) claims.

conclusionsDeath and permanent severe injury were common outcomes of perioperative pulmonary aspiration of gastric contents in this series of closed anesthesia malpractice claims. The majority of the patients who aspirated had either gastrointestinal obstruction or acute intraabdominal processes. Anesthesia care was frequently judged to be substandard. These findings suggest that clinical practice modifications to preoperative assessment and anesthetic management of patients at risk for pulmonary aspiration may lead to improvement of their perioperative outcomes. EDITOR’S PERSPECTIVE:

Indexed as

AnesthesiologyDatabases, FactualFemaleGastrointestinal ContentsHumansInsurance Claim ReviewMaleMiddle AgedRespiratory Aspiration

Identifiers

PMID34019629
OpenAlexW3161982356

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.