Evidence map›Paper›PMID 34019589›Full record

ArticlePloS one2021

Dynamical SPQEIR model assesses the effectiveness of non-pharmaceutical interventions against COVID-19 epidemic outbreaks.

Daniele Proverbio, Françoise Kemp, Stefano Magni, Andreas Husch, Atte Aalto, Laurent Mombaerts, Alexander Skupin, Jorge Gonçalves, Jose Ameijeiras-Alonso, Christophe Ley

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

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  8. Dynamics of epidemic diseases without guaranteed immunity.Journal of mathematics in industry · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Daniele ProverbioLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0002-0122-479X
Françoise KempLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-5845-293X
Stefano MagniLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0001-8649-3616
Andreas HuschLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Atte AaltoLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Laurent MombaertsLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Alexander SkupinLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Jorge GonçalvesLuxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.ORCID 0000-0002-5228-6165
Jose Ameijeiras-AlonsoDepartment of Mathematics, U Leuven, Leuven, Belgium.ORCID 0000-0002-4122-6992
Christophe LeyDepartment of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium.
University of Luxembourg · LUGhent University · BEKU Leuven · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Against the current COVID-19 pandemic, governments worldwide have devised a variety of non-pharmaceutical interventions to mitigate it. However, it is generally difficult to estimate the joint impact of different control strategies. In this paper, we tackle this question with an extended epidemic SEIR model, informed by a socio-political classification of different interventions. First, we inquire the conceptual effect of mitigation parameters on the infection curve. Then, we illustrate the potential of our model to reproduce and explain empirical data from a number of countries, to perform cross-country comparisons. This gives information on the best synergies of interventions to control epidemic outbreaks while minimising impact on socio-economic needs. For instance, our results suggest that, while rapid and strong lockdown is an effective pandemic mitigation measure, a combination of social distancing and early contact tracing can achieve similar mitigation synergistically, while keeping lower isolation rates. This quantitative understanding can support the establishment of mid- and long-term interventions, to prepare containment strategies against further outbreaks. This paper also provides an online tool that allows researchers and decision makers to interactively simulate diverse scenarios with our model.

Indexed as

Contact TracingCOVID-19HumansModels, StatisticalPhysical DistancingQuarantine

Identifiers

PMID34019589
PMCPMC8139462
OpenAlexW3163461246

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.